Antiseizure Medication
Gabapentin controls seizures in children receiving chemotherapy
Published in Pain and Central Nervous System Week, May 17th, 2004
"Hepatic clearance of chemotherapy drugs is increased by many antiepilepsy drugs." New-onset "seizures in children on chemotherapy are treated with gabapentin, a nonhepatic enzyme inducer," at the authors' institution. "The charts of all children given gabapentin for seizures were reviewed," wrote scientists at St. Jude Children's Hospital.
"At a median follow-up of 34 months, seizures were controlled in 74% of 50 children given gabapentin monotherapy as initial treatment: 91% of the leukemia group, 57% of the brain tumor group, and 75% of the other tumor group. Seizures were controlled...
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