Hypertension
Arterial baroreflex signals depend on neuronal NOS
Published in Pain and Central Nervous System Week, May 17th, 2004
"Because inhibition of neuronal nitric oxide synthase in the nucleus tractus solitarii blocks cardiovascular responses to activation of local glutamate receptors, and because glutamate is a neurotransmitter of baroreceptor afferent nerves," scientists in the United States "sought to test the hypothesis that neuronal nitric oxide synthase inhibition would block baroreflex transmission and cause hypertension.
In their study, W.T. Talman and colleagues at the University of Iowa "determined reflex heart rate responses to intravenous phenylephrine and sodium nitroprusside...
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