Susan Hasty, Publisher
Table of Contents . . . August 23rd, 2004
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Pain and Central Nervous System Week | Other Publications
Diabetic Neuropathy - Supporting sensory neurons may aid diabetic patients
Drug Delivery - Transdermal permeation of synthetic cannabinoids determined
Epilepsy - Effects of vagus nerve stimulation on cortical excitability determined
Knee Replacement - Obdurator nerve block enhances femoral nerve block analgesia
Neuroscience - Hepatitis A virus infection sparks acute disseminated encephalomyelitis
Addiction Medicine - Novel model improves assessment of methadone compliance
Adolescent Health - Many adolescent girls experience headache, stomachache, back pain and fatigue
Alzheimer Disease - "Tangled" rat provides landmark experimental model
Alzheimer Disease - Early clinical treatment can halt progression of AD
Alzheimer Disease - HIV survivors vulnerable to dementia?
Alzheimer Disease - Immune therapy "untangles" Alzheimer plaques
Alzheimer Disease - Mice overexpressing A-beta are incomplete model of Alzheimer disease
Alzheimer Disease - New drug treats both symptoms and cause of Alzheimer disease
Alzheimer Disease - Oakland facility may have found possible contributing cause of AD
Alzheimer Disease Therapy - Vaccine reduces A-beta levels in non-human primate
Amyotrophic Lateral Sclerosis - Orphan drug designation granted by FDA for drug candidate to treat ALS
Antiretroviral Therapy - Mental illness and sociological factors impact antiretroviral adherence
Arrhythmias - Diffuse T-wave inversions can occur with electroconvulsive therapy
Arthritis - A novel therapy of murine collagen-induced arthritis with soluble T1/ST2
Autism - Physiological treatment center uses LifeShirt to measure signs of autism
Awards - 2004 Alzheimer Award presented to Lester I. Binder
Bovine Spongiform Encephalopathy - Human mad cow infection may be more widespread than previously thought
Brain Aneurysm - 3D CT cisternogram useful for preoperative contour evaluation
Brain Cancer - 3-D irradiation of brain cancer in children can spare cognitive functions
Brain Cancer - 3-D irradiation of brain tumors in children spares IQ, memory
Brain Cancer - Clusters of alterations on PIK3CA gene found in brain cancers
Brain Cancer - Small molecule inhibitors thwart glioma growth
Brain Tumor - Nutritional rehabilitation may help growth in pediatric brain cancer patients
Brain Tumor - Permanently implanted device used for intratumoral chemotherapy in rat brain
Business & Finance - CHRONOGESIC maker reports increased Q2 revenue, updates development programs
Business & Finance - Medical device company announces financial results
Business & Finance - Neuroscience-based biotech updates Q2, reports $118 million net loss
Central Nervous System - Estrogen facilitates neurite extension via ApoE in mouse cortical neurons
Cerebral Palsy - United Cerebral Palsy extends resources, services through MetDESK
Cholesterol - Lipid association releases findings attitudes about over-the-counter statins
Collaborations - Target & marker discovery collaboration with Merck to focus on AD
Depression - Boomers warned to watch for signs of elderly depression
Depression - Depression traced to overactive brain circuit
Depression Therapy - Perospirone may enhance fluoxetine efficacy
Drug Abuse - Relationship between psychiatric disorders and addiction explored in report
Drug Addiction - Cocaine does not affect dopamine synthesis in rats
Drug Development - Drug developer receives approval for drug bringing 2004 total approvals to 10
Drug Development - Enrollment completed in clinical trial for Gaucher disease
Drug Development - Manhattan Pharmaceuticals, Inc., to file for IND for lingual spray sedative
Drug Development - Novel selective GSK-3beta inhibitors synthesized
Environmental Health - Hardness of drinking water studied as cardio-, cerebrovascular disease risk
Environmental Toxins - Study finds high mercury in lake fish
Epilepsy - Patent application filed for epilepsy compound
Erectile Dysfunction - FDA clears device for erectile dysfunction
Finance - Drug development company reports 2004 second quarter results
Finance - Neuromodulation device maker reports net income increases 48%
Finance - Pharma company specializing in neurodegenerative diseases secures financing
Finance - Strong second quarter for pharmaceutical company, 2004 to be very good year
Geriatrics - Use of statin drugs for Alzheimer treatment gaining wide attention
HIV/AIDS Infection - HIV/AIDS knowledge does not translate into perceived risk
HIV/AIDS Research - Cerebral synthesis of complement factors strongly upregulated in SIV infection
HIV/AIDS Research - HIV Tat protein prevents long-term potentiation in hippocampal CA1 region
HIV/AIDS-Associated Dementia - HIV associated neurodegeneration requires p53 in neurons and microglia
Headache and Migraine - Phase II trials for use of PreHistin to prevent atopic migraine begin
Heart Attack Prevention - Aspirin resistance test now available nationwide
Immunology - FDA accepts NDA for Xibrom
Legal Issues - Suit alleges Zoloft maker concealed evidence, misled doctors about drug safety
Lung Cancer - ADAM9 overexpression correlates with brain metastasis in NSCLC
Medical Marijuana - Medical marijuana initiative sparks debate
Mergers & Acquisitions - Imaging company acquires cardiovascular, neurovascular disease specialist
Multiple Sclerosis - FDA accepts BLA for ANTEGREN
Multiple Sclerosis - T-cell reactivity to immunodominant PLP peptides higher in women than men
Multiple Sclerosis Therapy - Daclizumab effective in patients failing to respond to interferon-beta
Myasthenia Gravis - IL-10-modified dendritic cells protect against autoimmune myasthenia gravis
Narcolepsy - Trial studying daytime sleepiness associated with narcolepsy progressing
Neurodegeneration - VEGF and bone marrow transplantation treat newborn mice with enzyme deficiency
Neurology - Hybrid neural system improves study of neuronal currents
Neuroscience - Brain trauma heightens TGFbeta RII expression on endothelial cells
Neuroscience - Cadmium blocks GABA-activated ion currents by raising intracellular Ca level
Neuroscience - Genomic effects of environmental enrichment characterized
Neuroscience - Orbit/MAST acts downstream of Abl in mediating axon guidance
Neuroscience - St. John's wort constituent stimulates hippocampal acetylcholine release
Neuroscience - Transdermal nitroglycerin safe, effective for subarachnoid hemorrhage treatment
Obstetrics - Maternal T3 and T4 levels in early pregnancy affect fetal brain development
Oligodendroglioma - Utility of immunohistochemistry in differential diagnosis determined
Osteoarthritis - Common drugs are ineffective after 2 weeks
Otology - Hearing where it's at: how humans and gerbils learn to locate sound
Pain Medicine - Diagnosis of painful total knee arthroplasty reviewed
Pain Medicine - Pupillary effects of opioids determined
Painkiller Addiction - West Virginia official says federal data on painkiller addiction not accurate
Panic Disorder - Gene polymorphism associated with panic disorder with agoraphobia
Parkinson Disease - New technologies aid in discovery of novel gene transcripts
Parkinson Disease - Screening tool could prevent wrong patients from receiving brain surgery
Perception - Study explains spatial orientation differences between sexes
Personnel - Biopharmaceutical company announces executive appointments
Personnel - CORLUX maker appoints David L. Mahoney to board of directors
Preeclampsia - Cytotoxic edema may evolve differently from pattern seen in cerebral infarction
Prion Disease - Prions found in skeletal muscle cells and papillae in the tongue
Prion Diseases - Synthetic prion causes neurological disease in mice
Restructuring - Medical technology company announces restructuring plans, reports results
Schizophrenia - Study links ACP-104 to improved cognition in schizophrenia patients
Spasticity Therapy - Rights to Zanaflex acquired from Elan
Spinal Cord Ischemia - Delta-opioid agonist SNC80 preserves rat hind-limb function
Spinal Cord Regeneration - Novel techniques promote recovery from spinal cord injury
Stem Cell Research - Amyloid-beta peptide has positive and deleterious actions in neurogenesis
Stem Cell Research - At single cell level ESC-derived neurons integrate into the host brain circuitry
Stem Cell Research - Chronic ethanol consumption transiently reduces neural stem cell proliferation
Stem Cell Research - Neural stem cells survive, migrate, differentiate in pre-clinical stroke study
Stem Cell Research - Neuronal cells can be specifically generated from bone marrow stromal cells
Stroke - Clinical targets show promise for minimizing effects of stress hormones
Stroke - Green mamba snake venom hormone may cause "second stroke"
Stroke - Statins decrease stroke incidence in people with coronary heart disease
Stroke - Stroke related and unrelated to pregnancy examined in reproductive-age women
Stroke Therapy - AM-36 neuroprotective in murine stroke model
Substance Abuse - Genes may be central to cocaine addiction
Tinnitus - Patients need not suffer in silence
Tobacco Use - Nicotine inhibits sulpiride-induced dopamine release in nucleus accumbens
Traumatic Brain Injury - New research calls for schools to be more aware of head injuries
Vertigo - New research explains lag in onset of common type of vertigo
Virology - How a killer virus emerged: changed environment + mutation = evolution
Wound Care - A little help from friends makes wounds heal faster
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