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Pain & Central Nervous System Week

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Pain Medicine



Study examined the nature of chest pain



February 21st, 2005

High-dose adenosine infusion provokes oscillations of chest pain without correlation to opioid modulation.

According to published research from Sweden, "Adenosine is a neuromodulator with both excitatory and inhibitory effects in different organs. High-dose adenosine infusion provokes chest pain in patients and healthy volunteers. [Our] study examined the nature of chest pain and whether it is modified by the R opioid receptor agonist (beta-endorphin) or a nonselective opioid antagonist (naloxone)."

B. Sadigh-Lindell and colleagues of the Karolinska Institute explained, "Ten healthy volunteers with a mean age of 26±3 years participated in the...


Source: Pain & Central Nervous System Week (2005-02-21)

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