Pain & Central Nervous System Week
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Activin Receptors
Receptor complexes studied, utility of a cell-free system revealed
February 21st, 2005
Recent research from the United States described the use of a cell-free system for the reconstitution and analysis of soluble inhibin and activin receptor complexes. "Activins and inhibins compose a heterogeneous subfamily within the transforming growth factor-beta (TGF-beta) superfamily of growth and differentiation factors with critical biological activities in embryos and adults. They signal through a heteromeric complex of type II, type I, and for inhibin, type III receptors," wrote E. Delre and colleagues, Harvard University. "To characterize the affinity," they continued, "specificity, and activity of these receptors (alone and in combination)...
Source: Pain & Central Nervous System Week (2005-02-21)
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