Published in Pain and Central Nervous System Week, October 17th, 2005
ADX10059, a negative allosteric modulator of the metabotropic glutamate 5 (mGlu5) receptor, is one of a new class of drugs being developed by Addex, that modulate the effect of the natural activator on its specific target. Compounds with this mechanism of action have the potential for an improved side effect profile and better efficacy, compared to existing therapies.
The study will be conducted in France and is a placebo-controlled single ascending dose study in up to 48 healthy...
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