Susan Hasty, Publisher
Table of Contents . . . November 21st, 2005
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Pain and Central Nervous System Week | Other Publications
Cancer Therapy - Central nervous system chemoprophylaxis in non-Hodgkin lymphoma requires standardization
Genetics & Genomics - Variation in genes influences clinical response to morphine
Neurology - T-lymphocyte movement through blood-central nervous system barrier is reviewed
Neuroscience - Scientists study chemical preconditioning as a way to help nerve cells withstand toxic attack, preserve function
Pain Management - Flavonoid treatment has little impact on pain or bleeding after ambulatory stapled hemorrhoidopexy
Addiction Medicine - Constella Group awarded $25 million contract to help prevent substance abuse
Addiction Medicine - Hythiam expands to Utah; PROMETA protocols now offered to patients at Cirque Lodge
Addiction Medicine - U.S. Institute of Medicine issues report on mental illnesses and drug addictions
Alzheimer Disease - Acute gamma-secretase inhibition improves contextual fear conditioning in mice
Alzheimer Disease - Fluorinated stilbene derivatives show promise for PET imaging of beta-amyloid plaques
Alzheimer Disease - Help is just a phone call away for individuals affected by memory loss
Neurology - New findings in neurology described
Alzheimer Disease - High-resolution serum proteomic profiling developed for Alzheimer disease detection
Alzheimer Disease - New scrapbooking approach to help families affected by Alzheimer disease
Alzheimer Disease Vaccine - Adenovirus vector induced an anti-inflammatory immune response
Alzheimer Disease Vaccine - Aldolase is target antigen in Alzheimer disease
Anesthesia - Anesthesia with pentobarbital rather than ketamine/xylazine may be preferred for echocardiography
Apoptosis - Immunosuppression by morphine-induced lymphocyte apoptosis did not occur
Neuroscience - Researchers publish new studies and findings in the area of neuroscience
Arthritis - Lifestyle choices may help control arthritis pain
Attention Deficit Hyperactivity Disorder - SPARLON, for treatment of ADHD in children and adolescents, receives approvable letter
Attention-Deficit Hyperactivity Disorder - Medication patch shown effective for attention-deficit hyperactivity disorder
Awards - LSU researcher receives $485,000 U.S.NIH grant to study Friedreich's ataxia
Back Pain - Stimulation system launched to diagnosing back and neck pain
Biomaterial - Osteogenic protein 1 putty may improve bone autograft outcome in lumbar fusion
Neuroscience - Studies advance knowledge in neuroscience research
Biomedical Engineering - Electrostatic microactuators were developed for neural microelectrode positioning
Bioterrorism - U.S. grants $20 million for developing compounds to treat radiation damage
Bipolar Depression - Development agreement to fund drug trial for bipolar depression
Botulism - Mass spectrometric method developed to differentiate botulinum neurotoxins
Brain Cancer - Chest CT and brain MRI provide optimal evaluation of patients with newly detected brain mass
Brain Cancer Therapy - Pemetrexed has limited distribution to brain
Brain Injury - Rat study of blood substitute in traumatic brain injury shows positive results
Business & Finance - Biotechnology company requests reconsideration pending delisting from Nasdaq
Cancer Clinical Trials - Recommended phase II dose for T900607 determined
Cancer Pain Management - Age and tumor type significantly influence transdermal fentanyl absorption
Cancer Risk Factors - Cell phone use not related to risk of acoustic neuroma
Cancer Therapy - Reports add new data to cancer therapy research
Cancer Therapy - Second-line chemotherapy showed modest activity in patients with hormone-refractory prostate cancer
Cardiomyocytes - Recent studies add new data to cardiomyocytes research
Cardiomyopathy - Valsartan decreases type I collagen synthesis in patients with hypertrophic cardiomyopathy
Cardiovascular Research - Propranolol inhibits the human ether-a-go-go-related gene potassium channels
Carpal Tunnel Syndrome - Topical analgesic patch effective in reducing pain of carpal tunnel syndrome
Cell Development - Sonic hedgehog is required for cardiac outflow tract and neural crest cell development
Cell Physiology - Hyperpolarization-activated cyclic nucleotide-gated channels are modulated by Src kinase
Chemotherapy - Chemotherapy induced toxic myelopathy
Chemotherapy - Intracavitary chemotherapy used to treat recurrent glioblastoma
Chemotherapy - Razoxane was combined with radiotherapy for treatment of melanoma brain metastases
Clinical Trials - Phase I study begins of triple reuptake inhibitor for major depression
Clinical Trials - Positive preliminary results reported from trial of inhaled narcotic analgesics
Contracts - Health software company signs $1.2 million contract with Sweetser
Coronary Artery Bypass - Radial artery harvesting doesn't cause neurologic hand dysfunction
Dental Care - Clinical pediatric study supports benefits of CompuDent in administering anesthetic injections to children
Dermatology - Three studies show investigational psoriasis therapy may be effective option
Developmental Biology - fgf8 signaling functions in left-right patterning of visceral organs and craniofacial skeleton
Diagnostics - Brain abscess and cystic brain tumor discriminated with perfusion MRI
Diagnostics - HPLC method simultaneously detects four antiepiletic drugs in human serum
Diagnostics - MDCT angiography replacing catheter angiography as initial evaluation standard
Diagnostics - MRI visual rating scale improves assessment of cholinergic pathway hyperintensities
Diagnostics - Minimally invasive breath ammonia test not suitable for diagnosis
Diet & Exercise - Dietary alpha-linolenic acid increases brain but not heart and liver docosahexaenoic acid levels
Disease Associations - Duplications and copy number variants of 8p23.1 are studied in heart defects
Drug Delivery - Novel microemulsion system shows promise for transdermal aceclofenac delivery
Drug Development - Atypical antipsychotics based on 8-substituted 3,4-dihydroquinolinones show promise
Drug Development - Lilly to support study of antagonist to curb weight gain from antipsychotic drugs
Drug Safety - High doses of ibuprofen can cause significant GI bleeding despite its safety profile
Electroencephalography - Independent component analysis improved recognition rates for four classifiers
Embolism - Cerebral embolism occurred after transcatheter arterial chemoembolization
Endocrinology - Neuroblasts migrate in response to endothelin-1 through involvement of endothelin type B receptors
Endocrinology - Travelers can avoid jet lag by resetting their body clocks
Epilepsy - Application filed for treatment of myclonic seizures in juveniles
Finance - Cancer vaccine maker records loss of $0.60 per share
Finance - Drug developer raises $29.4 million in series A financing
Finance - Medical device company reports 3 month revenue of $9.1 million
Generic Drugs - California pharma company authorized to distribute generic oxycodone tablets
Genetics & Genomics - Hippocampus and amygdala have distinct genomic responses to fear conditioning
Genetics & Genomics - Novel molecular karyotyping system submicroscopic chromosome alterations
Genetics & Genomics - Tryptophan hydroxylase 2 gene variants are associated with ADHD
Geriatrics - Survey reveals older Americans' attitudes toward sleep and healthy aging
Glioblastoma - Kinase genes are amplified in highly vascular brain tumors
Granulocytic Sarcoma - Granulocytic sarcoma manifested as multiple skeletal lesions
HIV/AIDS Pathogenesis - Research add new data to HIV/AIDS pathogenesis body of knowledge
Heart Failure - CorCap cardiac support device improves surgical outcome in patients with cardiomyopathy
Hospice - Patients indicated a dislike for questionnaires
Hypoxia - Supercooling varies glycogen, free glucose, and lactate in organs of Chrysemys picta
Imaging - Lesion size determines imaging accuracy
Imaging - fMRI reveals alteration of spatial working memory networks across adolescence and gender
Immunization - Immunization awareness organization supporting Tdap booster
Immunology - Recent findings in immunology provide new insights
Infections - Adequate control of postoperative pain prevented infections after lung cancer surgery
Influenza - Children with neurological and neuromuscular diseases should receive annual flu shot
Influenza - Neurological disease raises the risk of complications from flu
Ischemia - Heat stress increases the effectiveness of early ischemic preconditioning in spinal cord protection
Ischemia - Plaminogen activator gene polymorphism influences ischemic stroke
Medical Devices - Cochlear implantation improves speech capabilities in pediatric patients
Medical Devices - Medical technology company enhances monitoring of patient-controlled analgesia
Mental Health - Alzheimer's Foundation of America offers post-hurricane coping techniques
Mental Health - Developer of oxidative stress disorders treatments demonstrates mammalian aging is under the control of CLK-1 activity
Mental Health - University study shows genetic trigger is behind some cases of schizophrenia
Migraine Therapy - Oral naratriptan is effective for treatment of menstrually related migraine
Multiple Sclerosis - Animal model study shows drug compound effective on multiple sclerosis
Multiple Sclerosis Vaccine - IVIG reduces neurological abnormalities when given prophylactically
Muscular Dystrophy - New muscular dystrophy cooperative research centers are announced
Myocardial Infarction - Morphine enhances isoflurane-induced postconditioning against myocardial infarction
NeuroAIDS - 6-Chloro-2',3'-dideoxyguanosine decreases C1q synthesis and SIV burden in neuroAIDS
NeuroAIDS - Lithium protects neurons from secretions of HIV-1-infected monocyte-derived macrophages
Neurology - Findings in neurology provide new insights
Neurology - Generalized cable equation model developed for myelinated nerve fiber
Neurology - Novel rat model of mild cerebral concussion injury reveals impaired spatial learning
Neurology - Ras/MEK pathway is required for coordinate expression of GCH and TH genes in PC12D cells
Neurology - Retinal degeneration caused by rd1 mutation effects hyppocampal-dependent learning in mice
Neurology - Two antiphase oscillations occur in SCN of behaviorally split hamsters
Neurology - Ultrasound accelerated nerve regeneration when cells were seeded with PLGA conduits
Neurology - Vestibular vertigo may be common in the general population
Neuroscience - Apelin counteracts vasopressin secretion
Neuroscience - Dendrite changes may be involved in learning
Neuroscience - Pallidal neuron firing rates similar in Huntington and Parkinson disease patients
Neuroscience - People can rapidly reshape motor generalization to best learn a new movement task
Neuroscience - Researchers detail new studies and findings in the area of neuroscience
Neuroscience - The angiogenic chemokine CXCL12 has prognostic value in low-grade gliomas
Obesity - Findings help understanding of brain pathways' role in obesity development
Ophthalmology - Intraocular pressure must be considered when assessing glaucoma risk and corneal thickness
Ophthalmology - Neural networks may distinguish normal and glaucomatous visual fields
Ophthalmology - Pharma company executes agreement to promote treatment for dry eye disease
Opioids - Use of multiple opioids can lead to increased risk for dosing errors
Orthopedics - New licensing agreements to develop spacer implants for arthritis treatment
Orthopedics - Orthopedics-focused spine non-fusion company changes name to Paradigm Spine, LLC
Osteoarthritis - Blood-based osteoarthritis biomarker paper published
Pain Management - Arthroscopic treatment improves stability and reduces pain
Pain Management - Drug infusion systems company launches line of electronic infusion pumps
Pain Management - Etoricoxib provides safe and effective analgesia after joint replacement surgery
Pain Management - Marketing application submitted for U.K. approval of injectable pain treatment
Pain Management - Sonography-guided iliopsoas peritendinous injections have diagnostic and therapeutic utility
Palliative Care - Methotrimeprazine used in management of nausea and vomiting in advanced cancer
Parkinson Disease - Protein known to cause neurodegeneration may, at normal levels, offer protection
Parkinson Disease - Stem cell implantation shows beneficial effect on Parkinson disease
Patents - Lexapro patent litigation trial date rescheduled to March 15, 2006
Pediatric Neurology - Mechanisms that govern ICP may be disrupted during traumatic brain injury
Pediatric Stroke - Pediatric stroke protocol developed at Pennsylvania hospital
Philanthropy - Johnson & Johnson awards $40,000 to Hawaiian nonprofit to promote AAC device use by children
Physiology - Osmosensitive mechanisms contribute to the water drinking-induced pressor response in humans
Physiology - Researchers publish new studies and findings in the area of physiology
Postherpetic Neuralgia - Enrollment complete for phase II clinical trial for Gabapentin GR
Prions - Studies advance knowledge in prions research
Product Licensing - License agreement signed to develop and commercialize Aurora kinase inhibitors
Proteomics - German biotech company reports validation of therapeutic, anti-inflammatory NBE Protease in vivo
Proteomics - Researchers detail new studies and findings in the area of proteomics
Rheumatoid Arthritis - Butyrate appears to regulate TNFa at the mRNA level, making it a potential RA therapy
Rheumatoid Arthritis - Opposite immune responses explain different therapeutic effects in rheumatoid arthritis
Rheumatoid Arthritis - Synovial proteome microarrays provide diagnostic information for RA
Rhinitis - PreHistin significantly reduces allergy symptoms in 714-patient phase III clinical trial
Spinal Cord Injury - Antibody to IL-6R suppresses secondary injury and glial scar formation in spinal cord injury
Spinal Cord Injury - UCB transplantation improves functional recovery after spinal cord injury
Spinal Surgery - Company reports 100 have received implantable cervical artificial disc
Spinal Surgery - Spinal technology company reports 100 surgeons trained to use screw placement device
Stem Cell Disorders - Telomerase activity in MDS may be insufficient to compensate for telomere shortening
Stem Cell Research - Chronic intrathecal injections of a large volume of fluid increase mast cells in the CNS
Stem Cell Research - Clearance granted for phase I trial of neural stem cells to treat Batten disease
Stem Cell Research - Neural stem cell differentiation is dependent upon endogenous caspase-3 activity
Stem Cell Research - Neuroprotection by stem cell factor in cortical neurons involves Akt and NF kappa B
Stroke - NCAM-derived peptide FGL protects neurons from ischemic injury
Stroke - Women receive fewer diagnostic tests for ischemic stroke than men
Surgical Technology - 3D CT angiography of internal carotid artery facilitates endoscopic approach
Surgical Technology - Modified implantation approach preserves residual deep frequency hearing
Surgical Technology - New surgery technique used to remove formerly inoperable tumors from the cervical spine
Surgical Technology - Practice advisory on intraoperative awareness and brain function monitoring adopted
Surgical Technology - Single-photon emission CT and balloon occlusion show comparable hypoperfusion
Type 2 Diabetes - Over 60% of type 2 diabetics in Dallas, Texas, study missed blood sugar target
Urology - Heart rate variability in female patients with overactive bladder differs from normal controls
Urology - Percutaneous nerve stimulation leads have high bacterial contamination rate
Vaccines Vector - Researchers' data advance vaccines vector research
Vasculitis - Patients with hepatitis C-associated nerve lesions have altered immune response factors
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