Alzheimer Disease

Link discovered between long-term depression and changes in the AD brain

Published in Pain and Central Nervous System Week, February 27th, 2006

A lifetime history of depression is associated with increased plaques and tangles in the brains of those with Alzheimer's disease and more rapid cognitive decline, according to a study by researchers at the Alzheimer's Disease Research Center at Mount Sinai School of Medicine.

The study was published in the February 2006 issue of Archives of General Psychiatry.

Previous studies have linked depression and Alzheimer's disease. People with a lifetime history of major depressive disorder (MDD) may be more likely to be diagnosed with AD. In addition, both AD and MDD are likely to affect the brain's memory-related temporal lobes. MDD is likely to...

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Source: Pain and Central Nervous System Week (2006-02-27)

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