Schizophrenia
Nicotine downregulates dopamine D2 receptor availability in antipsychotic drug treatment
Published in Pain and Central Nervous System Week, February 27th, 2006
According to a study from The Netherlands, "Occupancy of dopamine D2 receptors by antipsychotic drugs depends on the individual availability of D2 receptors and on the dose and type of antipsychotic medication."
"It has been suggested that a low availability of these receptors may increase the risk for addictive behavior. This study aims to show that patients with relatively high occupancy of D2 receptors by antipsychotic drugs are more prone to nicotine consumption," wrote Haan L. de and colleagues from the...
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