Pain and Central Nervous System Week

Amyotrophic Lateral Sclerosis Research - Packard scientists announce first international gene search for typical ALS

Immunotherapy - Research uncovers signaling pathways in brain-immune system links

Pain Management - Study suggests tension headache may actually be TMJD

Statins - Statins may be useful in treatment of migraine headache

Alzheimer Disease - Alzheimer disease key angiogenesis elements are hampered by beta-amyloid

Alzheimer Disease - Prana Biotechnology moves forward with PBT2 phase IIa trial in Alzheimer disease patients

Alzheimer Disease - Prana receives promising report on PBT2 phase I trial; phase II trial in the works

Alzheimer Disease - Well-functioning lungs reduce risk of dementia

Anesthesia - Anesthetic depth is accurately monitored with either the bispectral index or response entropy

Anesthesia - The Seeing Optical Stylet may be superior to the gum elastic bougie

Angina - PET is used to determine dysfunction in patients with anginal pain and normal coronary angiogram

Apoptosis - Ischemia-induced apoptosis and neuronal injury is inhibited by procaspase binding

Apoptosis - Neuronal apoptosis is more strongly induced by less neurovirulent rabies vaccine strain

Apoptosis - Nucleocytoplasmic Pak5 shuttling regulates its antiapoptotic properties

Awards - D-Pharm selected for second consecutive year by Red Herring as a Top 100 European company

Awards - Distinguished USC doctor is recipient of 2006 Physician Recognition Award

Awards - Roche awards Excellence in Chemistry awards to 12 PhD candidates and two professors

Breast Cancer - Grant will be used to test the effect of Tibetan Yoga on women with breast cancer

Business & Finance - Corcept Therapeutics reports net loss of $6.7 million in first quarter

Business & Finance - Corgentech reports net loss of $14.6 million for first quarter

Business & Finance - Curis reports net revenues of over $2 million for first quarter

Business & Finance - Cypress Bioscience, Inc. reports net loss of approximately $3.5 million in first quarter

Business Update - Cytogen enters into QUADRAMET royalty buyout agreement with Berlex

Business Update - Sontra introduces updated transdermal glucose monitoring, topical lidocaine delivery system

Business Update - Synergetics introduces line of bipolar forceps for ophthalmic surgery, neurosurgery

Business Update - Two Tennessee CHY network hospitals select speech recognition and imaging software system

Business Update - USAN Council approves name lorcaserin hydrochloride for Arena drug candidate for obesity

Cancer Gene Therapy - Gene transfer of stromal cell-derived factor-1 suppresses murine tumor growth

Cardiovascular Disease - Hologic gets U.S. FDA clearance to use Discovery DXA System for detecting cardiovascular disease

Cardiovascular Disease - Lifestyle changes benefit GNB3*825T allele carriers most

Cardiovascular Research - $900,000 granted for first Canadian chair in hypertension prevention and control

Cardiovascular Research - Closing holes in the heart is an important treatment for young stroke patients, study finds

Cardiovascular Research - More data needed to determine whether holes in heart lead to stroke

Clinical Trials - Avanir's Neurodex phase III trial results published

Clinical Trials - Economic evaluation suggests nicorandil compares favorably with other heart disease interventions

Cognitive Science - VSM reports progress on using MEG for diagnosing Alzheimer and Parkinson

Diabetes Complications - Ciliary neurotrophic factor prevents acute lipid-induced insulin resistance

Diabetes Pathogenesis - Diabetes may interfere with synthesis of nitric oxide of corpus cavernosum nerves and endothelium

Diabetic Nephropathy - NephroGenex licenses Pyridorin for diabetic nephropathy and acute renal failure

Diabetic Neuropathy - Intraepidermal nerve fiber loss cannot explain pain in all diabetic neuropathy cases

Drug Abuse - Study confirms effectiveness of Vivitrol for alcohol dependence

Drug Development - Antibody-based assays for omega-conotoxin MVIIA have been developed

Drug Development - Avicena initiates creatine bioequivalencey study aimed at optimizing therapies

Drug Development - Chelsea Therapeutics seeks to develop Droxidopa for neurogenic orthostatic hypotension

Drug Development - Chugai Pharmaceutical files for additional indication for Actemra

Drug Development - Eisai will initiate phase I study for E2012, a potential treatment for Alzheimer disease

Drug Development - Maxygen achieves milestone in alliance with Roche for factor VIIa therapeutics

Drug Safety - Doctors widely prescribe drugs without adequate scrutiny, Stanford scientist finds

Endocrinology - Excess blood leptin does not diminish brain intranasal leptin uptake

Endocrinology - Genistein and methoxychlor alter mammary gland development in male rats

Endocrinology - Leptin required for uncoupling protein-1-independent thermogenesis during cold stress

Enzymology - Matrix-degrading proteases garner support from brain-derived neurotrophic factor

Epilepsy - Medical intractable epilepsy may be treated adjunctively with neurostimulation

Ewing Sarcoma - Ewing sarcoma palliated with radiation therapy

Ewing Sarcoma - ICE plus CAV were effective in treating patients with sarcoma family of tumors

Finance - Allergan Foundation donates $2 million to U of California Irvine for ophthalmology research

Finance - ChondroGene appoints David Tyler director, product development and quality assurance

Finance - Cortex reports net loss in first quarter

Finance - Hythiam reports first-quarter revenues of $653,000

Finance - Neurobiological Technologies, Inc. reports third quarter net loss of $3,863,000

Finance - Neurologix completes $12 million private placement

Finance - NMT Medical announces first-quarter 2006 total revenues increased to $6.9 million

Finance - Orthometrix, Inc. announces 59% increase in quarterly sales

Finance - Pain Therapeutics announces first quarter 2006 net income of $0.9 million

Finance - Questcor announces first quarter of 2006 net sales of H.P. Acthar Gel were $2 million

Finance - Sie Foundation, University of Colorado grant $1 million in Down syndrome research awards

Finance - Targeted Genetics announces one-for-ten reverse stock split

Finance - Titan reports a net loss in Q1 2006 of $4.7 million compared to $6.3 million a year ago

Finance - U.S. Army awards $2 million initially to Lexicon Genetics to study spinal muscular atrophy

Finance - VSM MedTech reports Q1 2006 revenue of $4.3 million up 5% from $4.1 million a year ago

Gene Research - Nerve tumors are linked to Nf1 heterozygosity and exaggerated angiogenesis

Generalized Anxiety Disorder - Predix's lead drug candidate for generalized anxiety disorder, PRX-00023, featured in journal

Genetics & Genomics - Chromosome 5 variations controls beta-cell mass expansion during hyperglycemia in mouse model

Genetics & Genomics - Common adrenergic receptor polymorphisms are novel risk factors for vasospastic angina

Genetics & Genomics - Drosophila PCNA gene promoter is antagonistically regulated by DREF and Cut

Genetics & Genomics - New genetic research method sheds light on drug metabolism

Geriatrics - Elderly blood pressure variability affects cognitive function

Glioma - Glioma not effectively treated with recommended phase 2 dose of irinotecan

Glioma - Glioma progression linked to DLK1 expression

Glioma - Glioma progression linked to MSH6 inactivation

Glioma - Putative mediator of growth arrest and death identified in malignant glioma cells

Glioma - Radiographic response assessment in newly diagnosed glioma patients validated

Glioma - Suppressed receptor expression inhibits U251 glioma cell growth

Healthcare Access - Federal data show community-based care leads to improved mental health services for children

Hematology - ADP-induced platelet aggregation was inhibited by disintegrins from rattlesnake venom

Imaging - Novadaq receives FDA clearance for changes in labeling of its intra-operative imaging system

Incontinence Device - ETHICON announces CE Mark approval of new device to treat female stress incontinence

Insomnia - Neurogen announces positive phase II clinical trial results for insomnia drug, NG2-73

Intellectual Development - Length of deprivation in infants found to affect intellectual development for years

Intubation - Fiberoptic nasotracheal intubation may cause more severe pressor and tachycardiac responses

Juvenile Arthritis - Study shows childhood arthritis raises risk of broken bones in later life

Leptomeningeal Leukemia - Leptomeningeal leukemia progression promoted by integrin activation on tumor cells

Leukemia - Central neurocytoma with concomitant cerebral involvement by acute lymphatic leukemia described

Market Analysis - Report suggests market for mixed urinary incontinence may favor novel product launches

Meningioma - Link between meningioma risk and GSTM3 alleles requires further edification

Menopause - Positive phase 3 trial results of transdermal spray for treating menopause symptoms reported

Mental Health - Lilly submits supplemental NDA to U.S. FDA for duloxetine in generalized anxiety disorder

Mental Health - Marketing authorization application filed in Europe for new schizophrenia treatment

Mental Health - Researchers reveal Prozac's target in the brain

Mergers & Acquisitions - Draeger Medical acquires De-Tec anesthesia service business

Mergers & Acquisitions - Questcor announces the acquisition of Doral for insomnia from MedPointe

Migraine Headaches - Study shows topiramate reduces days per month of suffering in chronic migraine patients

Multiple Sclerosis - Depression in MS patients is a clue to better treatment

Multiple Sclerosis - Glatiramer injection study showed 92% of RRMS patients still walking after 10 years on treatment

Multiple Sclerosis - Multiple sclerosis relapse correlates with high levels of angiogenesis protein