Pain and Central Nervous System Week

Nanotechnology - Superparamagnetic iron oxide nanoparticles interact with brain structures

Neurology - Scientists watch neurons within the brain of a living animal change in response to experience

Pain Management - Metamizol was superior to parecoxib and paracetamol for postoperative pain relief

Pain Management - New preclinical method to assess pain and analgesia has been developed

Parkinson Disease - Researchers examine mechanisms that may explain the causes of Parkinson disease

Aging - Cross-sectional study reports link between low B12 and cognitive impairment in older patients

Alzheimer Disease - Bronx, New York nursing home gets surprising results from Alzheimer video project

Alzheimer Disease - Celera discovers gene variants associated with Alzheimer disease

Alzheimer Disease - TorreyPines completes second phase 1 study of selective M1 agonist for treating Alzheimer disease

Amyotrophic Lateral Sclerosis - CytRx successfully completes patient dosing and follow-up in Phase IIa clinical trial for ALS drug

Anesthesia - Hypnosis index of spectral entropy is reproducible in neurosurgical patients

Anesthesia - Postoperative nausea, vomiting and pain are assessed after transsphenoidal surgery

Anesthesia - Sevoflurane and isoflurane anesthesia impair cerebrovascular CO₂ reactivity in diabetics

Aneurysms - Intracranial aneurysms treated with stent-assisted coil occlusion device

Angiology - CABG surgery with pericardial blood processing outcomes are assessed

Angiology - Monoamine uptake inhibitors block alpha7-nAChR-mediated cerebral nitrergic neurogenic vasodilation

Anxiety - New study shows potential of intranasal midazolam as sedative

Apoptosis - Herpes Simplex Virus-1 latency-associated transcript has anti-apoptotic function

Apoptosis - Mature oligodendrocytes rapidly process pro-nerve growth factor and do not undergo cell death

Apoptosis - Novel gene functions in Xenopus cell survival and anteroposterior patterning

Attention Deficit Hyperactivity Disorder - Shire files NDA with U.S. FDA for compound to treat adult attention deficit disorder

Autism - Autism verbal capability linked to error-related negativity amplitude

Autism - Pediatric Bioscience licenses technologies for early detection of autism; hires CEO

Awards - Prana cofounder Masters receives lifetime achievement award in Alzheimer research

Behcet Disease - Morphologic evidence of subclinical atherosclerosis was obtained in Behcet's disease patients

Brain Cancer - Brain cancer assessments based on angiogenesis patterns are limited by observer inconsistency

Brain Cancer - Glioma angiogenesis and proliferation are overpowered by metronomic temozolomide

Brain Cancer - Recurrent pediatric brain tumors treated by intraoperative radiotherapy with photon radiosurgery

Brain Function - Mice learn tasks that may help treat human psychiatric disorders

Brain Function - Researchers examine the effectiveness of meditation on early cognitive impairment

Brain Tumors - An amino acid transporter is a potential molecular target in astrocytic tumors

Brain Tumors - Malignant cerebral tumor diagnosis enhanced by perfusion and diffusion MRI

Burning Mouth Syndrome - Burning mouth syndrome can be a complex and frustrating condition to diagnose and treat

Business & Finance - Curis reports second quarter financial results

Business & Finance - Dyax Corp. reports net loss of $7.9 million for second quarter

Business Update - Boston Scientific treats 5000 chronic pain patients with neuromodulation technology

Business Update - GlaxoSmithKline marks 10 years of providing over-the-counter therapeutic nicotine products

Business Update - I-Flow inks contract with Broadlane for ON-Q PainBuster Post-Op Pain Relief System

Business Update - Mylan announces final approval for added strengths of transdermal vasometer systems

Business Update - Oxigene reports second-quarter 2006 operational and financial results

Business Update - Pharmacopeia presents at Canaccord Adams 26th annual summer seminar

Business Update - Vistakon to introduce new one-day contact lenses with water holding ability in U.S.

Cancer Gene Therapy - Gene transfer suppresses the invasive potential of human malignant gliomas

Cancer Pain Management - Medico-legal aspects of the use of fentanyl patches discussed

Cancer Therapy - PD-L1/PD-1 interactions negatively regulate T cell effector functions

Cardiology - Phrenic nerve injury after atrial fibrillation catheter ablation is characterized

Cardiopulmonary Resuscitation - Cerebral oxygenation readings during CPR by spectroscopy differ between skin and skull

Cardiovascular Research - Cardiac functions are altered by deletion of peroxisome proliferator-activated receptor-alpha

Cardiovascular Research - Cardiopulmonary bypass management and neurologic outcomes are reviewed

Cavernoma - Pediatric cerebral cavernomas feature angiogenic cytokines

Cell Biology - Circadian rhythm generated in a glioma cell line

Central Nervous System - Case of primary extranodal nasal-type natural killer/T cell lymphoma of the brain reported

Cerebrovascular Event - High C-reactive protein levels increase stroke or transient ischemic attack risk

Cocaine - Glutamatergic signaling may be a mechanism of cocaine behavioral effects

Collaborations - Ipsen and Tercica to enter into worldwide strategic collaboration in endocrinology

Degenerative Joint Diseases - TissueGene initiates phase 1 clinical trial with treatment for degenerative joint diseases

Dementia Therapy - Sugar and alcohol molecules are therapeutic for serpinopathies causing dementia and cirrhosis

Diabetes & Genetics & Genomics - High glucose activated polyol pathway and changed gene activity in immortalized Schwann cells

Diabetes Complications - Diabetes mellitus is associated with hepatic encephalopathy in patients with HCV cirrhosis

Diabetes Therapy - Neuroactive steroids prevent peripheral myelin alterations induced by diabetes

Diabetic Neuropathy - Oral magnesium administration prevents thermal hyperalgesia induced by diabetes in rats

Diabetic Neuropathy - Thermoregulatory sweating abnormality indicates early sympathetic damage in diabetic feet

Drug Safety - Cardiac safety profile of rivastigmine in Lewy body and Parkinson disease dementias is favorable

Dyslexia - Computer games detect early signs of autism and dyslexia in children

Encephalitis - Virus-specific CD4 T cells are pathogenic in acute encephalitis

Endocrinology - Mash1 is needed for generic and subtype differentiation of hypothalamic neuroendocrine cells

Epilepsy - Color vision, macular recovery time studied in epileptic adolescents

Epilepsy - Ketogenic diet monitoring is possible using subcutaneous microdialysis

Epilepsy - Propofol dosing in the treatment of refractory status epilepticus is assessed

Finance - Dutton Associates announces investment opinion, Amarin rating raised to Strong Speculative Buy

Finance - ExonHit Therapeutics announces first-half 2006 revenues up 46%

Finance - Eyeonics, Inc. reports revenues in Q2 2006 up 30% over year ago to $4.3 million

Finance - Hearing aid maker Sonic Innovations announces Q2 2006 net income up 19% from a year ago

Finance - Kyphon reports Q2 net sales of $101.1 million, an increase of 35%

Finance - Millennium Pharmaceuticals reports strong Q2 2006 results, progress in marketing Velcade

Finance - Orthofix announces record sales in second quarter 2006

Finance - Quigley Corporation reports Q2 2006 net sales of $6.2 million, down from $8.8 in Q2 2005

Finance - Sangamo BioSciences reports 2006 Q2 net loss of $3.3 million, revenue of $1.8 million

Finance - Sepracor reports Q2 2006 consolidated revenues of $264.4 million

Finance - SuperGen reports 2006 Q2 revenues of $24 million, up from $7.9 million in Q2 2005

Finance - TGen/SARRC Research receives $7.1 million in state appropriations funding for autism research

Gene Research - Different genes may cause autism in boys and girls

Gene Research - Family-specific approaches to the analysis of case-control family data described

Gene Research - Gene recombination can be temporally controlled in astrocytes

Gene Research - Gene variations may increase stroke risk for younger women

Genetics & Genomics - DSG2 mutations contribute to right ventricular dysplasia/cardiomyopathy

Geriatrics - Atrial fibrillation is a risk factor for brain hemorrhage in older patients

Geriatrics - Medical conditions can rob people of their balance

Geriatrics - Raloxifene treatment enhances brain activation in elderly males

Glioblastoma - Glioblastoma protein expression altered by radiotherapy

Glioblastoma - Telomerase inhibition impairs tumor growth in glioblastoma xenografts

Glioma Vaccine - Dendritic cells pulsed with glioma lysates increase survival of tumor-bearing mice

HIV/AIDS Progression - SIV Tat evolution correlates with AIDS progression during morphine-dependence

Healthcare Costs - Catheter ablation for atrial fibrillation patients at moderate stroke risk is cost-effective

Human Cytomegalovirus Vaccine - Researchers outline an innovative method for creating a human cytomegalovirus vaccine

Hunter Syndrome - U.S. FDA approves Shire's enzyme replacement therapy idursulfase for Hunter syndrome

Huntington Disease - Amarin completes target patient enrollment in phase III trial of Miraxion in Huntington disease

Huntington Disease - Sodium channel subunit down-regulation may be involved in neuritic degeneration

Hydrocephalus - Neuroendoscopic ventriculostomy mechanisms for hydrocephalus treatment failure are studied

Imaging - InfraScan enrolls first patients in brain hematoma detection trial

Imaging - Positron Corporation's affiliate Imaging PET Technologies records 150th sale of IS2 SPECT camera

Injury Prevention - Research into traumatic brain injuries supports helmet use for children and adults

Irritable Bowel Syndrome - Efficacy of treatments for irritable bowel syndrome is focus of review

Lymphoma - Primary spinal epidural lymphoma responded better to combined modality treatment than radiotherapy alone

Major Depressive Disorder - Adjunctive atomoxetine evaluated for residual fatigue in major depressive disorder

Market Analysis - Forty-eight percent of people experience constant pain

Medical Devices - Michigan neuropathy screening instrument offers a reliable test for diabetic neuropathy

Medicare - Community mental health system reports $304 million in uncompensated costs on Medicare drug benefit

Melanoma - Brain metastases in melanoma patients controlled by Gamma-Knife radiosurgery

Meningioma - Meningioma growth and invasion are hampered by tissue factor pathway inhibitor

Meningioma - Microcystic meningiomas overexpress matrix enzyme

Mental Health - Brain activity predicts depression treatment results before medication begins

Mental Health - Packard Children's Hospital offers tips to reduce back-to-school stress

Mental Health - Study shows many adults considering suicide are not getting mental health treatment

Migraine Pathophysiology - Migraine pathophysiology new findings are reviewed

Multiple Sclerosis - Biogen Idec, Elan announce availability of Tysabri to treat relapsing forms of multiple sclerosis