Pain and Central Nervous System Week

Glioblastoma - Glioblastoma linked to increased concentrations of transforming growth factor beta 2

Migraine Therapy - Sumatriptan acutely increases aortic blood pressure, stiffness, and augmentation index

Proteomics - Protein biomarker candidates may lead to diagnosis, treatment for age-related diseases

Tay-Sachs Disease - Gene therapy was effective in authentic model of Tay-Sachs-related diseases

Alcohol Use - Chronic alcohol exposure can affect brain protein expression

Alcohol Use - Long-term abstinence may resolve many of the neurocognitive deficits associated with alcoholism

Alzheimer Disease - Enrollment complete in U.S. trial of selective amyloid lowering drug for Alzheimer disease

Alzheimer Disease - Fruit and vegetable juice consumption may reduce the risk of Alzheimer disease

Alzheimer Disease - Scientists closer to early Alzheimer diagnosis

Alzheimer Disease - Stress significantly hastens the progression of Alzheimer disease

Amyotrophic Lateral Sclerosis - Massachusetts General, Harvard select Illumina HumanHap300 BeadChips for ALS research

Analgesia - Over-the-counter analgesics appear safe and effective in the treatment of colds and flu

Anesthesia - Laryngeal mask airway guided insertion is superior for use by new anesthesia residents

Angiomyxoma - Case of aggressive angiomyxoma presenting as a retrovesical tumor described

Arthritis Therapy - Osteoarthritis pain treatment strategies are reviewed for safety in African Americans

Atherosclerosis - Cardiovascular disease risk is linked to soluble CD40 ligand, interleukin-6, and oxidized LDL

Autism Research - Newly discovered gene mutation explains cognitive deficits associated with autism

Autism Research - Serotonin transporter gene is not associated with autism

Awards - Endocrine Society honors Cleveland Clinic physician-researcher Charis Eng, MD, PhD, with award

Awards - Foundation for Neurofeedback and Applied Neuroscience recognizes study of brain and neurofeedback

Balamuthia Encephalitis Diagnostics -  Balamuthia amoebic encephalitis in Portugal diagnosed by immunofluorescence and PCR

Brain Cancer - National Brain Tumor Foundation funds research into glioblastoma multiforme

Brain Cancer - Study links lead exposure to brain cancer in adults

Brain Metastases - Brain metastases survival improved after gamma knife radiosurgery in selected patients

Business & Finance - Cardiogenesis announces results for second quarter and first half of 2006

Business & Finance - Diversified business portfolio helps Medtronic report strong first quarter earnings per share

Business Update - BrainStorm targets treatment of stroke with its adult stem cell technology

Business Update - CoGenesys announces worldwide license agreement with Vegenics Limited

Business Update - Elekta receives U.S. FDA clearance for Leksell Gamma Knife Perfexion

Business Update - Vystar Corporation, Revertex Malaysia team to produce nonallergenic safe rubber latex

Cancer Therapy - Glioma management by convection-enhanced delivery discussed

Cancer Therapy - Valeant giving Managing Chemotherapy Side Effects For Dummies to patients and caregivers

Cardiology - Anesthetic preconditioning occurs when protein kinase upregulates proangiogenic cytokines

Cardiopulmonary Resuscitation - Thrombolytic agents improve outcome for patients treated with cardiopulmonary resuscitation

Cardiovascular Disease - Arteriovenous communications in peripheral femoral arterial system in diabetes is uncommon

Cardiovascular Research - Merck's early analyses show thrombotic cardiovascular events similar in NSAID, COX-2 drugs

Carpal Tunnel Syndrome - New clinically documented carpal tunnel product stops wrist pain

Central Nervous System Tumors - Central nervous system tumors low morbidity linked to use of N-butyl cyanoacrylate liquid adhesive

Cerebral Arteriovenous Malformations - Pediatric cerebral arteriovenous malformations treated by radiosurgery

Chemotherapy - Tumor response to chemotherapy predicted by Na-23 MRI and water ADC measurements

Clinical Trials - EpiCept completes patient enrollment in European Phase III clinical trial for LidoPAIN SP

Cognition - Impaired memory is not necessarily associated with sedation

Critical Care Medicine - Orotracheal intubation with fiberoptic bronchoscope does not reduce hemodynamic response

Dermatology - EFoodSafety.com Inc. reports completion of clinical trials on scar cream

Diabetes Control - Multigenerational survey shows changing behaviors is greatest challenge in managing diabetes

Diabetic Neuropathy - Exercise training can modify natural history of diabetic peripheral neuropathy

Diabetic Neuropathy - Increased oxidative stress contributes to diabetic neuropathy

Diabetic Ulceration - Diabetic foot wound risk appears to increase for those wearing poorly fitting shoes

Diagnostics - Susceptibility-weighted imaging used to characterize tumors

Drug Development - Neuren announces favorable Phase 2a pharmacokinetic and safety data for Glypromate

Drug Development - Neurodegenerative disease research receives funding at Wayne State University

Drug Development - Questcor files sNDA for treatment of infantile spasms with H.P. Acthar gel

Embryonic Stem Cell Research - Silk matrices are suitable biomaterials for embryonic stem cell encapsulation

Epilepsy - Corpus callosotomy use as palliative treatment for epilepsy in children is reviewed

Epilepsy - Electrical stimulation improves seizure outcome in patients with Lennox-Gastaut syndrome

Epilepsy - Hypothalamic hamartoma is effectively treated with gamma knife surgery

Epilepsy - Magnetoencephalography role in pediatric epilepsy surgery is reviewed

Epilepsy - Tuberous sclerosis complex-associated epilepsy management is reviewed

Facilities - Spinal implant company Facet Solutions moves to new corporate headquarters in Logan, Utah

Finance - Stem Cell Therapeutics Corp. reports net loss in 6 months ended June 20, 2006

Gastroenterology - Wyeth, Progenics initiate phase 2 trial of methylnaltrexone for opioid-induced constipation

Genetics & Genomics - Novel insertion of a rearranged element detected in the dystrophin gene

Glioblastoma - Glioblastoma patients demonstrate the safety of cannabinoid therapy

Glioma - Cannabinoid glioma therapy targets not only receptors on tumor, but on other cell types

Glioma - Glioma patients tolerated a combination of EGFR and mTOR inhibitors

Glioma - Glioma surgery might benefit from individual functional mapping, connectionism, and plasticity

Hepatitis C Virus - Hepatitis C virus gene expression involves multidrug resistance protein upregulation

Imaging - Enhanced washout of ¹²³I-MIBG occurs in autonomic failure, Parkinson, and dementia

Immunotherapy - Granulocyte macrophage colony stimulating factor is a promising therapy for autoimmune lung disease

Ischemia - Epicardial action potentials and response to ischemia-reperfusion are unchanged by brain death

Ischemia - Transient forebrain ischemia is associated with tau factor hyperphosphorylation

Ischemic Stroke - Cardiac glycosides provide neuroprotection against ischemic stroke

Juvenile Myoclonic Epilepsy - U.S. FDA approves Keppra as adjunctive therapy in juvenile myoclonic epilepsy

Leukemia - Acute lymphoblastic leukemia prognosticated by CALCA promoter hypermethylation

Lung Cancer - Lung cancer suppressed by RNA interference targeting pituitary transforming gene

Lymphoma - Central nervous system lymphoma responded to topotecan salvage therapy

Marketing - Imagenetix launches retail branding program; former Pharmavite executives to lead campaign

Medical Devices - Biowave gets 510(k) clearance of its pain therapy system

Medical Devices - Computer-assisted devices offer patients an alternative to traditional physical rehabilitation

Medical Devices - Pediatric preformed cuffed tracheal tubes need to be improved

Medullary Thyroid Carcinoma - Medullary thyroid carcinoma with liver metastases treated by chemoembolization

Mental Health - Neuropeptide-deficient mice exhibit anxiety and antidepressant-like activity

Mental Health - Research team is analyzing brain alterations in schizophrenia patients

Moyamoya Syndrome - Moyamoya syndrome risk is higher in NF-1 patients due to lower radiation-dose threshold

Multiple Sclerosis - Caraco gets U.S. FDA approval to market Baclofen

Multiple Sclerosis - Multiple sclerosis damage is found in normal brain tissue

Multiple Sclerosis - Subclinical left ventricular dysfunction is suggested in multiple sclerosis patients

Neuroblastoma - Neuroblastoma subtypes respond to mitogen-activated protein kinase inhibition

Neurogenesis - Notch1 expression spatiotemporally correlated with neurogenesis in developing nervous system

Neurology - Brain scan study finds there is no single God spot in the brain

Neurology - Focal cortical dysplasia treatment requires total lesionectomy with complete focus resection

Neurology - Preoperative brain mapping allows surgeons to target tumors for more successful surgery

Neurology - Researchers examine the region of the brain thought to be devoted to face recognition

Neurology - Researchers identify brain cells used to categorize images

Neurology - Scientists discover mechanism of manganese-induced neurological dysfunction

Neurology - Traffic fines fund new research on spinal cord injury

Neuroscience - Aspm specifically maintains symmetric proliferative divisions of neuroepithelial cells

Neuroscience - Expression of neuronal transporter increased by transcription regulatory factor

Neuroscience - Intracellular amphetamine stimulates dopamine transporter trafficking

Neuroscience - Nervous system repair is augmented when EphA4 generates vascular formation

Neuroscience - Neuropeptide S amino acid residues crucial for receptor activation identified

Neuroscience - Synaptotagmin silencing inhibits fast exocytosis and endocytosis

Obesity Complications - BMI linked to white-coat effect, hypertension, and baroreflex sensitivity in youth