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Alzheimer Disease

New alzheimer disease findings from University of Leuven, Flanders Interuniversity Institute of Biotechnology described

Published in Pain and Central Nervous System Week, November 13th, 2006

Scientists discuss in "Amyloid excess in Alzheimer's disease: what is cholesterol to be blamed for" new findings in Alzheimer disease . "A link between alterations in cholesterol homeostasis and Alzheimer's disease (AD) is nowadays widely accepted. However, the molecular mechanism/s underlying such link remain unclear," scientists in Leuven, Belgium report.

"Numerous experimental evidences support the view that changes in neuronal membrane cholesterol levels and/or subcellular distribution determine the aberrant accumulation of the amyloid peptide in the disease. Still, this view comes from rather contradictory data supporting the...

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