Patents
European Patent Office upholds key Isis patent protecting antisense structures
Published in Pain and Central Nervous System Week, January 15th, 2007
The patent claims broadly cover antisense drugs with "chimeric" or "gapmer" structures, including Isis' proprietary second-generation structures and the compositions of numerous other antisense compounds. More specifically, the claims cover a class of antisense compounds, any of which is designed to have a sequence of phosphorothioate-linked nucleotides having two regions of chemically modified RNA flanking a region of DNA. This design, along...
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