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Alzheimer Disease

New findings reported from Charite University, Max Delbruck Center for Molecular Medicine describe advances in alzheimer disease

Published in Pain and Central Nervous System Week, January 15th, 2007

A new study, "Cognitive and physical activity differently modulate disease progression in the amyloid precursor protein (APP)-23 model of Alzheimer's disease," is now available. "In aging mice, activity maintains hippocampal plasticity and adult hippocampal neurogenesis at a level corresponding to a younger age. Here we studied whether physical exercise and environmental enrichment would also affect brain plasticity in a mouse model of Alzheimer's disease (AD)," researchers in Berlin, Germany report.

"Amyloid precursor protein (APP)-23 mice were housed under standard or enriched conditions or in cages equipped with a running wheel. We assessed beta-amyloid plaque load,...

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