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Stem Cell Research

New findings from New York Medical College, Department of Cell Biology in the area of stem cell research described

Published in Pain and Central Nervous System Week, February 26th, 2007

Data detailed in "Purinergic signaling regulates neural progenitor cell expansion and neurogenesis" have been presented. "Neural stem and progenitor cells typically exhibit a density-dependent survival and expansion, such that critical densities are required below which clonogenic progenitors are lost. This suggests that short-range autocrine factors may be critical for progenitor cell maintenance," scientists writing in the journal Developmental Biology report.

"We report here that purines drive the expansion of ventricular zone neural stem and progenitor cells, and that purine receptor activation is required for progenitor cells to be maintained as such. Neural...

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