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Neurological Disease

Scientists Produce Functioning Neurons from Human Embryonic Stem Cells

Published in Pain and Central Nervous System Week, August 20th, 2007

Scientists with the Institute of Stem Cell Biology and Medicine at UCLA were able to produce from human embryonic stem cells a highly pure, large quantity of functioning neurons that will allow them to create models of and study diseases such as Alzheimer’s, Parkinson’s, prefrontal dementia and schizophrenia.

Researchers previously had been able to produce neurons - the impulse-conducting cells in the brain and spinal cord - from human embryonic stem cells. However, the percentage of neurons in the cell culture was not high and the neurons were difficult to isolate from the other cells.

UCLA’s Yi Sun, an associate professor of psychiatry and...

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