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Parkinson Disease
Scientists at National Taiwan Normal University publish new data on Parkinson disease
November 19th, 2007
According to a study from Taipei, Taiwan, "Mutations in the glucocerebrosidase ( GBA) gene have recently been identified as contributing to the development of Parkinson disease ( PD) in Ashkenazi Jews To investigate whether this finding can be confirmed in a Taiwanese population, we conducted a case control study in a cohort of 518 PD patients and 339 controls for the three common GBA mutations in Taiwan, L444P, RecNciI and R120W, using PCR restriction enzyme assay and DNA sequencing Heterozygous GBA mutations were detected in 16 PD patients ( 3.1%) and four controls ( 1.2%)." "Although this difference was not statistically significant ( p = 0.0703), the average age at...
Source: Pain & Central Nervous System Week (2007-11-19)
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