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Pain & Central Nervous System Week

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Central Nervous System Disease Cell Biology



Scientists at Charite University, Institute of Cell Biology and Neurobiology report research in central nervous system disease cell biology



November 19th, 2007

Investigators publish new data in the report 'TLR2 and caspase-8 are essential for group B Streptococcus-induced apoptosis in microglia.' "Microglia, the resident innate immune cells of the CNS, detect invading pathogens via various receptors, including the TLR. Microglia are involved in a number of neurodegenerative diseases in which their activation may be detrimental to neurons," researchers in Berlin, Germany report.

"It is largely unknown how this potentially deleterious action can be countered on a cellular level. We previously found that the interaction of TLR2 with group B Streptococcus (GBS), the most important pathogen in neonatal bacterial meningitis,...


Source: Pain & Central Nervous System Week (2007-11-19)

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