Arthritis
Research conducted at Y. Sun and co-researchers has updated our knowledge about arthritis
Published in Pain and Central Nervous System Week, December 24th, 2007
In this recent study, researchers in the United States conducted a study "To extend the lifespan of rheumatoid arthritis fibroblast-like synoviocytes (RA FLS) using human telomerase catalytic subunit (hTERT) and to test the hypothesis that longterm culture of hTERTRA FLS may display a disease-specific gene expression pattern. RA 516 FLS were transduced by hTERT and the replicative properties of hTERT-RA 516 FLS were evaluated by repeated expansion."
"Gene expressions in hTERT-RA 516 FLS (passage 8) were compared with the gene expressions in hTERT-osteoarthritis (OA) 13A FLS (passage 8) by microarrays and RT-PCR. After continuous expansion in culture for an additional 4...
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