Published in Pain and Central Nervous System Week, December 24th, 2007
"Entacapone used as an adjunct to regular or controlled-release levodopa preparations increased ON-time and reduced OFF-time by I to 2 h daily in Parkinson's disease patients with wearing-off. The daily levodopa dose could also be reduced. Entacapone was generally well tolerated. Dopaminergic adverse events, such as dyskinesia and nausea, could usually be handled by...
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