Alzheimer Disease

Scientists at Vanderbilt University publish new data on Alzheimer disease

Published in Pain and Central Nervous System Week, December 24th, 2007

"Medial temporal lobe atrophy ( MTA) is a sensitive radiologic marker for Alzheimer disease ( AD) and associated with cognitive impairment. The value of MTA in the oldest old (> 85 years old) is largely unknown," scientists in Netherlands report.

"A total of 132 formalin-fixed brains from the Vantaa 85 + community-based study were subjected to postmortem MRI. Visual ratings of MTA were determined in a blinded fashion and compared with neuropathologic findings and clinical assessment ( dementia according to Diagnostic and Statistical Manual of Mental Disorders-III-R). A strong relationship was found between MTA scores and Alzheimer pathology ( p< 0.001). The...

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Source: Pain and Central Nervous System Week (2007-12-24)

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