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Alzheimer Disease

Cancer-related protein may play key role in Alzheimer's disease

Published in Pain and Central Nervous System Week, March 24th, 2008

Tampa, FL (Feb. 27, 2008) -- The cancer-related protein Akt may profoundly influence the fate of the tau protein, which forms bundles of tangled nerve cell fibers in the brain associated with Alzheimer's disease, reports a new study led by researchers at the University of South Florida and the Mayo Clinic in Jacksonville, FL.

The study was published online Feb. 21 in the early edition of the Proceedings of the National Academy of Sciences. The findings may provide another piece of the puzzle in figuring out how tau proteins can poison nerve cells in the brain.

Akt is known to increase cancer cell survival capability and has become a target in the...

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