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Myositis

Reports outline myositis research from Ohio State University, Center for Molecular Neurobiology

Published in Pain and Central Nervous System Week, March 24th, 2008

Data detailed in 'Casein kinase 1 alpha associates with the tau-bearing lesions of inclusion body myositis' have been presented. According to recent research from the United States, "Inclusion body myositis and Alzheimer's disease are age-related disorders characterized in part by the appearance of intracellular lesions composed of filamentous aggregates of the microtubule-associated protein tau. Abnormal tau phosphorylation accompanies tau aggregation and may be an upstream pathological event in both diseases."

"Enzymes implicated in tau hyperphosphorylation in Alzheimer's disease include members of the casein kinase 1 family of phosphotransferases, a group of...

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