Lupus Genetics
Studies from London School of Hygiene and Tropical Medicine have provided new information about lupus genetics
Published in Pain and Central Nervous System Week, May 19th, 2008
A new study, 'Familial clustering of non-nuclear autoantibodies and C3 and C4 complement components in systemic lupus erythematosus,' is now available. According to a study from London, the United Kingdom, "To determine whether key features of systemic lupus erythematosus (SLE), namely, production of non-nuclear antibodies (anti-C1q and anticardiolipin antibodies [aCL]) and depletion of complement components C3 and C4, aggregate in families. In addition, we examined relationships between anti-C1q and C3 and C4 levels."
"The study cohort comprised 1,037 predominantly white (82%) nuclear families in which at least 1 member had SLE. Associations of antibody measurements...
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