Alzheimer Disease

New Alzheimer disease research from N.S.M. Schoonenboom and co-researchers described

Published in Pain and Central Nervous System Week, July 7th, 2008

According to a study from Netherlands, "Decreased amyloid P (1-42) (A beta 42) and increased (phosphorylated) tau in cerebrospinal fluid (CSF) are considered to be a reflection of plaques, tangles, and neuronal degeneration in Alzheimer's disease (AD). Atrophy of the medial temporal lobe (MTA) 011 magnetic resonance imaging (MRI) reflects neuronal loss in this area."

"To compare diagnostic accuracy of CSF biomarkers and NITA in AD versus controls. A beta 42, tau and tau phosphorylated at threonine 181 (Ptau-181) were measured in CSF from 61 AD patients and 32 controls by sandwich enzyme-linked immunosorbent assay. A CSF biomarker profile for AD was constructed. NITA was...

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Source: Pain and Central Nervous System Week (2008-07-07)

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