Pain & Central Nervous System Week
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Epilepsy
Studies from Yale University, Medical Department describe new findings in epilepsy
September 1st, 2008
According to recent research from the United States, "Temporal lobe epilepsy (TLE) is associated with smaller hippocampal volume and with elevated extracellular (EC) glutamate levels. We investigated the relationship between the hippocampal volume and glutamate in refractory TLE patients." "We used quantitative MRI volumetrics to measure the hippocampal volume and zero-flow microdialysis to measure the interictal glutamate, glutamine, and GABA levels in the epileptogenic hippocampus of 17 patients with medication-resistant epilepsy undergoing intracranial EEG evaluation. The relationships between hippocampal volume, neurochemical levels, and relevant clinical factors...
Source: Pain & Central Nervous System Week (2008-09-01)
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