Alzheimer Disease Risk Factors
Findings from University of Bonn, Department of Psychiatry broaden understanding of Alzheimer disease risk factors
Published in Pain and Central Nervous System Week, November 17th, 2008
Fresh data on Alzheimer disease are presented in the report 'CETP polymorphisms influence cholesterol metabolism but not Alzheimer's disease risk.' "Cholesteryl ester transfer protein (CETP) is a component of the high density lipoprotein (HDL). Variations in the CETP gene may cause CETP deficiency, which is characterized by decreased mass and activity of the protein as well as altered HDL and LDL levels," scientists in Bonn, Germany report.
"We investigated the effect of three putative functional CETP polymorphisms (-1946 VNTR, C-629A and I405V) on the risk of Alzheimer's disease (AD) and on cholesterol, lathosterol and 24S-hydroxycholesterol levels in CSF and plasma of...
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