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Pain & Central Nervous System Week

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Alzheimer Disease



Study data from E.C. Petrie and colleagues update understanding of Alzheimer disease



June 15th, 2009

According to recent research published in the journal Archives of Neurology, "Alterations in cerebrospinal fluid (CSF) tau and beta-amyloid peptide 1-42 (A beta(42)) levels and rates of cerebral glucose metabolism (CMRglu) on fluorodeoxyglucose positron emission tomography (FDG-PET) occur years before clinical symptoms of Alzheimer disease (AD) become manifest, but their relationship remains unclear. To determine whether CSF AD biomarker levels and CMRglu in healthy individuals correlate in brain structures affected early in AD. Cohort study."

"Alzheimer disease research center. Twenty individuals without dementia aged 46 to 83 years. Lumbar CSF sampling and...


Source: Pain & Central Nervous System Week (2009-06-15)

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