Pain & Central Nervous System Week
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Anesthesiology
New anesthesiology findings from J. Villar and co-authors described
July 13th, 2009
"Previous experimental studies of ventilator-induced lung injury have shown that positive end-expiratory pressure (PEEP) is protective. The authors hypothesized that the application of PEEP during volume-controlled ventilation with a moderately high tidal volume (V-T) in previously healthy in vivo rats does not attenuate ventilator-induced lung injury if the peak airway pressure markedly increases during the application of PEEP," scientists writing in the journal Anesthesiology report. "Sixty healthy, male Sprague-Dawley rats were anesthetized and randomized to be mechanically ventilated for 4 h at (1) V-T of 6 ml/kg, (2) V-T of 20 ml/kg, or (3) V-T of 20 ml/kg...
Source: Pain & Central Nervous System Week (2009-07-13)
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