Pain & Central Nervous System Week
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Anesthesiology
Research from Karolinska University has provided new data on anesthesiology
July 13th, 2009
"Nondepolarizing neuromuscular blocking agents (NMBAs) are classic competitive-inhibitors at the muscle nicotinic acetylcholine receptor (nAChR). Although the fetal subtype muscle nAChR has been extensively studied at a molecular level, less is known about the interaction between nondepolarizing NMBAs and die human adult muscle nAChR," scientists in Stockholm, Sweden report. "The aim of this study was to investigate die effect of clinically used nondepolarizing NMBAs at human adult muscle nAChRs and die mechanisms behind die inhibition. Human subunits for the adult alpha(1)beta(1)delta epsilon muscle nAChR were cloned and expressed into Xenopus oocytes and thereafter...
Source: Pain & Central Nervous System Week (2009-07-13)
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