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Pain & Central Nervous System Week

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Hemorrhagic Shock



New hemorrhagic shock study results reported from D.M. Wu et al



July 13th, 2009

In this recent report published in the journal Critical Care Medicine, researchers in the United States conducted a study "To evaluate the use of a Na+/H+ exchanger (NHE-1) inhibitor as a cardioprotective adjunct therapy to low-volume resuscitation in two different rat models of traumatic hemorrhagic shock. Experimental, prospective study."

"Medical center research laboratory. Sprague Dawley male rats. Series 1: femur fracture was induced in anesthetized rats, followed by pressure-controlled hemorrhage (40 mm Hg for 20 minutes) and resuscitation. Groups: 1) no therapy; 2) 15 mL/kg hetastarch; and 3) 3 mg/kg benzamide,...


Source: Pain & Central Nervous System Week (2009-07-13)

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