Pain & Central Nervous System Week
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Taeniasis
Findings from M. Zimic et al in taeniasis reported
July 20th, 2009
"Neurocysticercosis, an endemic parasitic disease in most developing countries, is caused by Taenia solium and compromises the human central nervous system. Cathepsin L-like proteases are secreted by several parasites including T solium and constitute important antigens for immunodiagnostics," scientists in the United States report. "A protein fraction with cathepsin L-like activity was purified from the cysticercus fluid by size exclusion and ion exchange chromatography. Cathepsin L-like activity was measured fluorometrically by detecting the hydrolysis of the fluorogenic substrate Z-Phe-Arg-AMC. The purified protein fraction included antigens of 53 and 25 kD that were...
Source: Pain & Central Nervous System Week (2009-07-20)
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