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Massachusetts Institute of Technology

Rats' mental 'instant replay' drives next moves

Published in Pain and Central Nervous System Week, September 7th, 2009

Researchers at MIT's Picower Institute for Learning and Memory have found that rats use a mental instant replay of their actions to help them decide what to do next, shedding new light on how animals and humans learn and remember.

The work will appear in the Aug. 27 issue of the journal Neuron.

"By understanding how thoughts and memories are structured, we can gain insight into how they might be disrupted in diseases and disorders of memory and thought such as Alzheimer's and schizophrenia," said study author Matthew A. Wilson, the Sherman Fairchild Professor of Neuroscience at the Picower Institute. "This understanding may lead to new methods of...

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