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Alzheimer Disease Therapy

Study data from V. Leduc et al provide new insights into Alzheimer disease therapy

Published in Pain and Central Nervous System Week, December 7th, 2009

Current study results from the report, 'Involvement of paraoxonase 1 genetic variants in Alzheimer's disease neuropathology,' have been published. "Evidence suggests that the genes involved in brain lipid homeostasis are of particular relevance for Alzheimer's disease (AD) etiology. Among these genes, that encoding paraoxonase 1 (PON1) has gained newfound interest from a public health perspective, as recent studies have suggested that PON1 L55M and Q192R genetic variants might affect individual susceptibility to environmental events, such as exposure to cholinesterase inhibitors," scientists writing in the European Journal of Neuroscience report.

"Cholinesterase...

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