Bupivacaine Therapy

Reports summarize bupivacaine therapy research from J. Mauch and co-authors

Published in Pain and Central Nervous System Week, February 1st, 2010

According to recent research published in the British Journal of Anaesthesia, "Origin of electrocardiographic (ECG) alterations during intravascular injection of local anaesthetic solutions is controversial. The aim of this study was to elucidate whether epinephrine, bupivacaine or their combination is responsible for ECG alteration."

"Forty-five piglets were randomized into three groups. After induction of general anaesthesia using sevoflurane and peripheral venous cannulation, the trachea was intubated, the lungs were artificially ventilated, and anaesthesia was maintained by sevoflurane. Under steady state 0.2 ml kg(-1) and after 10 min 0.4 ml kg(-1) of one of...

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Source: Pain and Central Nervous System Week (2010-02-01)

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