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Hormones

New findings from Nagasaki University describe advances in hormones

Published in Pain and Central Nervous System Week, February 1st, 2010

Researchers detail in 'Parathyroid hormone 2 receptor is a functional marker of nociceptive myelinated fibers responsible for neuropathic pain,' new data in hormones. According to recent research published in the Journal of Neurochemistry, "We have previously demonstrated that parathyroid hormone 2 (PTH2) receptors are expressed in dorsal root ganglion (DRG) neurons and that its endogenous agonist tuberoinfundibular peptide of 39 residues (TIP39) causes nociceptive paw flexor responses after intraplantar administration. Here we found that the PTH2 receptor is selectively localized on myelinated A-, but not unmyelinated C-fibers using immunohistochemical labeling, based on PTH2...

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