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Studies from Texas Children's Cancer Center describe new findings in life sciences in children

Published in Pain and Central Nervous System Week, February 1st, 2010

Research findings, 'Neurodegenerative central nervous system Langerhans cell histiocytosis and coincident hydrocephalus treated with vincristine/cytosine arabinoside,' are discussed in a new report. "Central nervous system (CNS) complications of Langerhans cell histiocytosis (LCH) include mass lesions and a neurodegenerative (ND) syndrome with ataxia, dysarthria, dysmetria, learning and behavior difficulties and/or characteristic changes on brain MRIs. Hydrocephalus has rarely been reported in LCH," scientists in the United States report.

"LCH lesions of the orbit, mastoid and temporal bones ('CNS-Risk' lesions) and diabetes insipidus predispose patients to ND-CNS-LCH....

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