Small-vessel Disease
Investigators at University Medical Center release new data on small-vessel disease
Published in Pain and Central Nervous System Week, April 12th, 2010
According to recent research from Netherlands, "Cerebral white matter lesions (WMLs), due to small vessel disease, can be regarded as an early ''silent'' sign of hypertensive cerebral end-organ damage. As haptoglobin (Hp) phenotype has earlier been associated with symptomatic vascular disease, we now examined the relationship between Hp phenotype and asymptomatic cerebral small vessel disease, manifested by deep and periventricular WMLs, in hypertensive patients."
"We determined Hp phenotype using starch gel electrophoresis in 152 hypertensive patients without symptomatic vascular disease. We found 26 (17.1%) Hp1-1, 89 (58.6%) Hp2-1 and 37 (24.3%) Hp2-2. Volumes of deep...
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