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Stroke

Study results from H.Y.J. Wang and colleagues broaden understanding of stroke

Published in Pain and Central Nervous System Week, September 13th, 2010

"Stroke, a deleterious cerebrovascular event, is caused by a critical reduction in the blood flow to the brain parenchyma that leads to brain injury and loss of brain functions. The inflammatory responses following ischemia often aggravate the neurological damage," scientists writing in the journal Rapid Communications in Mass Spectrometry report.

"Several pro-inflammatory mediators released after stroke are closely related to the metabolism of phospholipids. In this study we directly profiled the changes in phospholipids in the infarcted rat cerebral cortex 24 hours after middle cerebral artery occlusion (MCAO) using matrix-assisted laser desorption/ionization...

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