Parkinson's Disease

Data on Parkinson's Disease Published by Researchers at University Hospital

Published in Pain and Central Nervous System Week, November 14th, 2011

2011 NOV 14 -- "Mutations in the LRRK2 gene are the most common genetic cause of Parkinson's disease, with frequencies displaying a high degree of population-specificity. Although more than 100 coding substitutions have been identified, only seven have been proven to be highly penetrant pathogenic mutations," scientists writing in the journal Parkinsonism & Related Disorders report.

"Studies however are lacking in non-white populations. Recently, Lrrk2 p.Q1111H (rs78365431) was identified in two affected Hispanic brothers and absent in 386 non-Hispanic white healthy controls. We therefore screened this variant in 1460 individuals (1150 PD patients...

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Source: Pain and Central Nervous System Week (2011-11-14)

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