Epilepsy
Findings from Harbin Medical College Provide New Insights into Epilepsy
Published in Pain and Central Nervous System Week, November 21st, 2011
2011 NOV 21 -- According to the authors of recent research from Heilongjiang, People's Republic of China, "Brain-derived neurotrophic factor (BDNF) plays a critical role in many aspects of neuronal biology and hippocampal physiology and pathology, and has been implicated as a potential therapeutic target in temporal lobe epilepsy (TLE). BDNF total mRNA and its six transcripts were compared in the hippocampal tissue of TLE patients with or without hippocampal sclerosis (HS) by real-time fluorescence quantitative polymerase chain reaction."
"Excitatory actions induced by BDNF on hippocampal cells were investigated by whole-cell patch-clamp recordings....
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