Ischemia

Reports Outline Ischemia Research from Max Planck Institute

Published in Pain and Central Nervous System Week, December 5th, 2011

2011 DEC 5 -- According to the authors of recent research from Cologne, Germany, "Oxygen therapy (OT) with hyperbaric oxygen (HBO) or normobaric hyperoxia (NBO) improves the oxygenation of penumbral tissue in experimental ischemic stroke. However, whether this results in the improvement of energy metabolism is unclear."

"We investigated the effect of both OTs on tissue acidosis and on ATP production. Beginning 25 min after filament middle cerebral artery occlusion (MCAO), mice breathed either air, 100% O-2 (NBO), or 100% O-2 at 3 ata (HBO) for 60 min. Regional tissue pH was measured using the umbelliferone fluorescence. Regional ATP concentration was...

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Source: Pain and Central Nervous System Week (2011-12-05)

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