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Parkinson's Disease

Data on Parkinson's Disease Discussed by Researchers at Institute of Clinical Neurobiology

Published in Pain and Central Nervous System Week, December 26th, 2011

2011 DEC 26 -- According to the authors of a study from Vienna, Austria, "Parkinson disease (PD) is a multisystem neurodegenerative disorder clinically characterized by motor and non-motor (NM) symptoms. The causes of NM symptoms in PD, many of which antedating motor dysfunction, are multifocal and unlikely explained by single lesions."

"They include olfactory, autonomic, sensory, skin, sleep, visual, neuropsychiatric, and other manifestations. Most NM features in PD are related to alpha-synuclein pathology which, in addition to the dopaminergic striatonigral system, involves non-nigral brainstem nuclei, sympathetic, parasympathetic, enteric and pelvic...

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