Stem Cell Research
Investigators at Kyoto University Zero in on Stem Cell Research
Published in Pain and Central Nervous System Week, January 2nd, 2012
2012 JAN 2 -- Investigators publish new data in the report "Deficiency of mDia, an actin nucleator, disrupts integrity of neuroepithelium and causes periventricular dysplasia. 'During development of the central nervous system, the apical-basal polarity of neuroepithelial cells is critical for homeostasis of proliferation and differentiation of neural stem cells. While adherens junctions at the apical surface of neuroepithelial cells are important for maintaining the polarity, the molecular mechanism regulating integrity of these adherens junctions remains largely unknown," researchers in Kyoto, Japan report.
"Given the importance of actin cytoskeleton in...
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