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Depression

Studies from Central South University Update Current Data on Depression

Published in Pain and Central Nervous System Week, February 20th, 2012

2012 FEB 20 -- A new study, "Ferulic acid-induced anti-depression and prokinetics similar to Chaihu-Shugan-San via polypharmacology," is now available. "Selective serotonin reuptake inhibitors (SSRIs), one of popular antidepressants as 'one-compound-one-target' paradigm, cannot but discontinue because of inhibiting gut movement. Traditional Chinese medicine (TCM) Chaihu-Sugan-San (CSS) can simultaneously exert anti-depression and prokinetics," investigators in Changsha, People's Republic of China report.

"From this thread, we aimed to find a new antidepressant with polypharmacological mechanisms. In vivo antidepressive and prokinetic comparisons between CSS...

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