Published in Pain and Central Nervous System Week, February 20th, 2012
"Here, we investigated how LCN2 influences neuronal phenotypes by using primary cortical neuronal cell cultures and neuroblastoma cell lines as a model. When exposed to LCN2 protein, neurons and neuroblastoma cells were sensitized to cell death evoked by nitric oxide, oxidative stress, and tumor necrosis factor-a (TNF-a). A forced expression of lcn2 in glia enhanced...
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