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Pharma Investments, Ventures and Law Weekly

Susan Hasty, Publisher

Table of Contents . . . March 14th, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Pharma Investments, Ventures and Law Weekly | Other Publications

Abiomed, Inc. - Product revenues increase 17% for cardiovascular device maker

Acuity Pharmaceuticals - Ophthalmic pharmaceutical company announces completion of financing round

Advancis Pharmaceutical Corp. - Pharmaceutical company reports loss of $0.29 per share

Alaris Medical Systems, Inc. - Drug delivery company's debt upgraded by Moody's

Alcon, Inc. - Sales grow 13.7% for pharmaceutical company

Alexion Pharmaceuticals, Inc. - Boess named VP, chief financial officer at pharmaceutical firm

ArQule, Inc. - Cancer drug maker reports loss of $0.18 per share

Aradigm Corporation - Drug delivery company reports 8.6% decrease in contract revenue

AtheroGenics, Inc. - Inflammatory diseases drug maker reports quarterly loss of $0.43 per share

Avanir Pharmaceuticals - Pharmaceutical company reports loss of $0.09 per share

Avigen, Inc. - Hemophilia treatment developer reports yearly loss of $1.28 per share

Barr Pharmaceuticals, Inc. - Pharmaceutical company board announces stock split

BioAdvance - Pennsylvania biotech greenhouse invests $3M in regional enterprises

BioDelivery Sciences International - Negotiations proceed on deal to formulate new type of aspirin

Biogen Idec - Biotech company reports 19% revenue growth for 2003

AFx inc. - Microwave surgical cardiac ablation developer acquired by Guidant

AGY Therapeutics, Inc. - Cathepsin B identified as important in mediating nerve cell death

ATNG, Inc. - New premenstrual syndrome supplement pack launched

Aarhus Municipal Hospital - Growth hormone appears to limit fracture risk in people with acromegaly

Abbott Laboratories - The LCx HCV RNA quantitative assay possesses several key attributes

Abmaxis, Inc. - Biopharmaceutical company names Shirley Liu Clayton chief executive officer

Accelrys, Inc. - Insight II and Catalyst now available on Linux

Affitech AS - Norwegian Radium Hospital receive FUGE grant to develop new anticancer agents

Alfred I. Du Pont Hospital for Children - The risk of acute pancreatitis is increased in children after spinal fusion

Allied Healthcare Products, Inc. - Respiratory care products company reports profitable 2Q

American Academy of Dermatology - Laser therapy prevents acne from graduating to scars

AngioDynamics, Inc. - FDA clears SpeedLyser infusion catheter

AstraZeneca - Survey finds many women stop or reduce asthma drugs during pregnancy

Aut Even Hospital - Agents aimed at wound healing elements could treat choroidal neovascularization

Avant Immunotherapeutics, Inc. - Immunotherapeutics firm announces $25M in equity financing

Baker Medical Research Institute - ACE inhibitors ameliorate connective tissue growth factor-induced retinopathy

Baylor College of Medicine - Hormone found to protect bones

BioReliance - Invitrogen completes acquisition

BioTime, Inc. - Blood products firm reports repayment of debentures

Bioorganic Chem. & Mol. Vector Systems, Avignon - THAM-derived cotelomers bearing thalidomide units stop new vessel growth

Bristol-Myers Squibb Co. - Data presented on potential new class of antiretroviral therapy

Can-Fite BioPharma - Ashleigh Palmer named new chief business officer at biotech company

Cardiac Science, Inc. - Defibrillator maker secures line of credit

Caremark Rx, Inc. - FTC clears way for merger of drug benefits companies

Carlos III Institute of Health, Madrid - Efavirenz-induced sleep abnormalities evaluated

Catharina Hospital, Eindhoven - Angiogenesis is difficult to quantify in oral cancers

Centocor, Inc. - Remicade shows promising results in psoriatic arthritis study

Chang Gung Memorial Hospital - Image fusion helps resolve discrepant findings between FDG-PET and MRI/CT

Change Technology Partners, Inc. - Neurologix completes merger

Charlotte Orthopedic Research Inst. - Osteolysis in posterior stabilized TKA is best detected with oblique films

Chelsea & Westminster Hospital - Synacthen Depot offers no advantages for treating postdural puncture headache

ChemBridge Research Laboratories - High-throughput medicinal chemistry deployed in alliance

City Hospital Nottingham - Digital mammography has not yet improved cancer detection rates

Cochin Hospital, Paris - Biomarkers of acute coronary artery disease reviewed

Columbia University - Mother's exposure to lead linked to schizophrenia in children

Conceptus, Inc. - Device maker reports sales of $2.3M in fourth

Correlogic Systems, Inc. - Mitsui makes equity investment in proteomics company

DaVita, Inc. - Gary Beil named interim CFO of DaVita

Deakin University - Hypothalamic genes implicated in Psammomys obesus obesity identified

Disease Prevention - Medicine may be handled by post office in national emergency

Drug Use - New test could help reduce unnecessary antibiotic use

Erasmus Medical Center - Link found between parkinsonism and dementia

Erciyes University - Effects of homocysteine on left ventricular hypertrophy in pediatric CRF clarified

Florida State University - Protein synthesis necessary for dendritic spine proliferation in adult brain

FlowMedica, Inc. - Device company names Vartan Ghazarossian president and CEO

Fremantle Hospital - Prophylactic ondansetron won't alleviate fentanyl-induced itching during labor

Frost & Sullivan - Awareness, understanding of IBS key to promoting new drugs

Gen-Probe Inc. - Diagnostics company reports strong financial results for Q4 and full year 2003

Genelabs Technologies, Inc. - Enrollment complete in confirmatory phase III clinical trial of Prestara

Genencor International, Inc. - Biotech company reports 2003 and fourth quarter financial results

GenoMed, Inc. - New approach may provide prompt recovery from bird flu

Graz University - SCT with voriconazole treatment feasible for AML with pulmonary aspergillosis

Hillman Cancer Center - Sulforaphane reduces PC-3 xenografts in vivo in a murine model

Hong Kong Univ. of Science & Technology - Solid-phase synthesis of cyclic decapeptide antibiotic streptocidins reported

Human Genome Sciences, Inc. - Albuferon maker reports increased net loss in 2003

INSERM U546, Paris - Self-peptide with superagonist activity blocks type 1 diabetes

INSERM U556, Lyon - Vibroacoustography holds promise for brachytherapy metal seed imaging

Inst. of Medical & Veterinary Science, Australia - Poly(A) binding protein binds AU-rich RNA via RNA-binding domains 3 and 4

Instituto Portuguese de Oncologia - Can early experiences predispose to hormonal disorders later in life?

Intuitive Surgical, Inc. - Robotics company reports record $27.6 million fourth quarter sales, up 30%

Isotechnika, Inc. - Company granted United States patent for cyclosporine antibodies

Istituto Orhtopedico Gaetano Pini, Milan - COX inhibitors compared for heterotopic ossification following arthroplasty

Istituto Superiore di Sanita - Vaginal infection with influenza A elicits immune response to HIV epitope

Jefferson Medical College - Jefferson researchers uncover biochemical clues to how cells migrate in embryos

Jikei University -  Helicobacter pylori has been implicated in the formation of liver cancer

Kendle International, Inc. - Research company reports increased fourth quarter revenues

Kobe University - Multiple anastomoses may reduce risk of thrombosis in free-flap transfer

Kyushu Institute of Technology - ProTherm, version 4.0, is thermodynamic database for proteins and mutants

LEO Pharma AS - The in vivo chamber angiogenesis assay measures angiogenic activity in mice

Lee Pharmaceuticals - Consumer products company increased gross revenues in first quarter

Louisiana State University - Intracoronary abciximab in coronary stenting may be better than i.v method

Lubeck Medical School - Tumor-based vaccine shows promise

McGill University - Post-thrombotic syndrome often complicates deep venous thrombosis

Medical Research Council, Cambridge - New lipophilic cation conjugates direct antisense agents to the inner cell

Methadone - Nebraska aims to protect children from methadone laboratories

Montreal Neurological Institute & Hospital - Widespread nerve fiber damage associated with fatigue

Mt. Sinai Medical Center - Clip markers can migrate after imaging-guided directional vacuum-assisted biopsy

Natl. Inst. of Advanced Industrial Science, Hyogo - Cultured alumina ceramics could prevent aseptic loosening of joint implants

NewYork-Presbyterian Hospital - Study finds vasectomy reversal highly effective, even after 15 years

NexTherapeutics, Inc. - Harvard inks letter of intent to acquire assets of antibody development company

Nutrition - Government computerizes calorie plan

Nutrition 21, Inc. - Nutritional supplements developer reports fiscal second quarter results

Oita University - A new gene carrier steers interleukin-12 to solid tumors

Ortec International, Inc. - Frozen OrCel promotes superior healing in venous leg ulcers, study shows

PHT Corporation - LogPad electronic patient diary to be used in postop pain clinical trial

Panacos Pharmaceuticals, Inc. - Human clinical trials of HIV maturation inhibitor to commence

Pfizer, Inc. - Federal appeals court upholds dismissal of Zoloft lawsuit

Pharmasset, Inc. - Phase II HIV study results of Reverset announced

Physiometrix, Inc. - Medical device manufacturer announces 2003 financial results

Postpartum Depression - Magellan identifies barriers to diagnosis, treatment of postpartum depression

Progen Industries Ltd - Lung cancer compound phase II trial commences

Quality Partners of Rhode Island - Signed consent requirement for influenza vaccination should be eliminated

RAND Corp. - Choosing hospice care raises federal program costs for last year of life

Ranbaxy Pharmaceuticals Inc. - Benazepril Hydrochloride Tablets approved for marketing

Recom Managed Systems, Inc. - Life sciences company announces new director of business development

Reddy's Laboratories - FDA plans expedited evaluation of AmVaz NDA

Royal College of Surgeons England - Working party reports on feasibility of facial transplantation

Royal Free Hospital, London - Specialty nurses benefit patients with neuroendocrine tumors

SEQUENOM Inc. - Novel mass spectrometry assay aids genotype identification

Scientific Inst. of Public Health, Belgium - Meta-analysis suggests HPV testing helps identify potential cases

Seoul National University Hospital - BiCONTACT revision stems with distal interlocking screws prove satisfactory

Serenex, Inc. - Drug discovery and pharmaceutical companies sign research agreement

Siemens Medical Solutions - Healthcare costs tops list of Americans' concerns

SinoFresh HealthCare, Inc. - Pharmaceutical company announces new chief financial officer

Skejby University Hospital - Cardiac troponin I mutation linked to idiopathic dilated cardiomyopathy

Society of Critical Care Medicine - Docs aim to reduce blood infection deaths

Solvay Pharmaceuticals, Inc. - FDA approves EstroGel transdermal gel for estrogen therapy

Sontra Medical Corporation - Skin permeation device facilitates rapid skin anesthesia within 5 minutes

St. Anna Hospital, Ferrara - Contrast-enhanced sonography guides transthoracic biopsy of lung lesions

Technical University of Liberec - Centrality indices characterize fat deposition in youngsters

Toyama Medical & Pharmaceutical Univ. - Pathogenetic tropism of varicella-zoster virus to human hepatocytes reported

Turku University - Myocardial perfusion not linked to peripheral endothelial function

U.S. Centers for Disease Control & Prevention -  Taenia solium antigen diagnostic for cysticercosis characterized

U.S. Centers for Disease Control & Prevention - Infection with Ebola virus persists under conditions of partial immunity

U.S. Centers for Disease Control & Prevention - More needs to be done to fight heart disease in young people

U.S. Department of Agriculture - Nitric oxide mediates anti-TB effects of vitamin D

U.S. Food & Drug Administration - Putrescine indicates decomposition in penaeid shrimp

U.S. National Institutes of Health - Electrostatics affect antigen recognition in chronic beryllium disease

Ukraine's Health Ministry - Ukraine criticizes U.N. decision to suspend funding for HIV/AIDS

Univ. College Hospital, Galway - Lack of cytogenetic response after imatinib treatment predicts relapse

Univ. Medical Center Utrecht - HIV-1 trans-activator protein affects pathogenesis of HIV-1 infection

Univ. Medical Center, Ljubljana - Computer program helps with planning gastric cancer surgery

Univ. of California, Berkeley - Community-acquired pyelonephritis is linked to drug-resistant E. coli

Univ. of California, Los Angeles - Update on the 2004 Database of Interacting Proteins reported

Univ. of California, San Francisco - Retroviral replication system aids HIV TAR study

Univ. of Medicine & Dentistry of New Jersey - Studies: Tazarotene is well tolerated

Univ. of North Carolina - Fetal mouse brain cells self-destruct when maternal folate levels are deficient

Univ. of Roma La Sapienza - Amine oxidases and tumors are correlated

Univ. of Southern California - Breast cancer risk significantly reduced in association with soy intake

Univ. of Southern California - Children with history of diabetes have reduced beta-cell function

University Hospital, Mainz - [18F]FDG-PET identifies patients ready for reconstructive surgery

University of Alabama - Surface layer protein EA1 is not component of Bacillus anthracis spores

University of Bologna - Real-time SYBR green PCR useful for HIV viremia measurement

University of Cambridge - Hedgehog-independent pathway identified for oligodendrocyte development

University of Essex - Glycation end products accumulate in kidney, retina, and peripheral nerve

University of Frankfurt - Antibiotic prophylaxis in aseptic orthopedic surgery is evaluated

University of Glasgow - British children become sedentary at young age

University of Hong Kong - Adiponectin attenuates protease inhibitor-induced dyslipidemia

University of Illinois - Fitness can improve thinking among aging

University of Iowa - Equine cloning's triple play sheds light on calcium, cell signaling

University of La Laguna - RAPD method allows Leishmania species differentiation

University of Malawi - Food tastes stronger when you're hungry

University of Massachusetts - Perinuclear HIV RNA release mediated by hRIP

University of Munich - Mantle cell lymphoma treatment reviewed

University of Natal - GBV-C infection has protective effect in HIV+ mothers

University of Padova - Treatment for endocrine disease: Is something missing?

University of Padua - Mast cells localize near blood vessels in the human area postrema

University of Paris-South - CTP biosynthesis inhibitors augment 3TC efficacy

University of Pavia - Apolipoprotein A phenotypes mark CHD familial aggregation

University of Pennsylvania - Gene therapy could lead to super athletes

University of Pittsburgh - A cell-mediated approach to sFlt-1 gene therapy targets thyroid cancer

University of Pittsburgh - Hepatocyte growth factor gene therapy improves islet transplantation outcomes

University of Vienna - Genetic screening counseling should be offered to infertility patients

University of Washington - Exposure to low-level magnetic fields causes DNA damage in rat brain cells

University of Washington - Stem cells found in adults may repair nerves

University of Zagreb - Dental and minor physical anomalies reveal youth with developmental disorders

Virax Holdings, Ltd. - VIR201 data presented at conference

Virgen del Rocio Univ. Hospital - Genotypic resistance after abacavir, efavirenz salvage treatment characterized

Wakayama Medical University - Rapid bone loss is a transient and unfixed phenomenon

Wake Forest University - Premature babies of anxious moms more likely to have worse development outcomes

Washington University - In utero exposure to alcohol appears to boost risk of psychiatric disorders

World Health Organization - WHO adds Fujian flu to vaccine list for next winter

Yale University - Cytoskeletal protein 4.1G binds to loop of A1 adenosine receptor

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