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Pharma Investments, Ventures and Law Weekly

Susan Hasty, Publisher

Table of Contents . . . May 16th, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Pharma Investments, Ventures and Law Weekly | Other Publications

Abiomed, Inc. - Option grant to new CEO reported under NASDAQ marketplace rule

Advanced Magnetics, Inc. - Nanobiotech company reports loss of $0.07 per share

Affymax, Inc. - Peptide drug maker completes Series C financing, adds new board member

Agentase, LLC - Biocatalyst maker receives $100,000 investment

Aksys, Ltd. - Dialysis systems developer files registration statement with SEC

AngioGenex, Inc. - Oncology company completes bridge financing

Avanir Pharmaceuticals - Pharmaceutical company files shelf registration statement

Axon Instruments, Inc. - Microarray licensing agreement signed

Bio-One Corporation - Majority control of Chinese glucose maker acquired

Business & Finance - Purchase of medical advisory services business assets announced

Caraco Pharmaceutical Laboratories - Pharmaceutical firm repays $6M loans

Cardiokine, Inc. - Heart disease drug maker completes $37M private equity financing

Connetics Corporation - Pharmaceutical company expects first quarter profit

Corcept Therapeutics, Inc. - Psychiatric drug developer announces initial public offering

Corus Pharma - Pharmaceutical firm raises $60M to advance clinical programs

3M - Aldara deemed approvable by U.S. FDA

A.P. Pharma, Inc. - Phase I trial of APF530 initiated as adjunct to chemotherapy

Abbott Laboratories - Agreement expanded for molecular diagnostics tests

Academic Medical Centre, Amsterdam - Subtype-specific transcriptional promoters determine replication rate

Alere Medical, Inc. - Davina C. Lane joins board of directors of care-management company

Andhra University -  Datura metel seeds exhibit hypoglycemic effects in diabetic rats

Arizona State University - Aaptamine derivatives show antitumor and antimicroibal activity

Arizona State University - Marine sponge constituent cribrostatin 6 bactericidal against S. pneumoniae

Arizona State University - Single chain antibody fragments inhibit aggregation of alpha-synuclein

Asaf Harofeh Medical Center - Major factors guide prenatal genetic testing among Israeli Moslem women

Atkins Nutritionals, Inc. - Low carb diet expert warns consumers about product frenzy

Baylor College of Medicine - Extrapancreatic insulin-producing cells found in multiple organs

Bentley Pharmaceuticals, Inc. - Approval granted to market a generic version of sertraline in Spain

BioElectronics Corporation - Device maker commences trading under symbol BIEL

BioPoint Solutions, Inc. - Biotech IT firm appoints Karen Moore chief science officer

BioRexis Pharmaceutical Corporation - Ragavan named VP of clinical and regulatory affairs at pharmaceutical firm

BlueCross BlueShield - Insurance giant says it's fighting $50 billion in fraud

CAS Medical Systems, Inc. - NIH grant will support development of non-invasive blood pressure monitors

CalbaTech, Inc. - Cooperative research program developing pathogen chip hits milestone

Cancer Treatment - Oklahoma House approves funds for cancer treatment

Catalan Oncology Inst., Barcelona - Celiac disease is not associated with lymphoma risk

Catholic University of Louvain - Antioxidant defense mechanisms stem non-alcoholic steatohepatitis progression

Catholic University of Louvain - Novel molecular assay quantifies HIV-2 viremia

Charite-University Medicine Berlin - Cross-fostering to diabetic rat dams affects body weight regulation

Christie Hospital, Manchester - Gefitinib shows promise in treating non-small cell lung cancer

Chung Shan Univ. Hospital, Taichung - Thallium-201 SPET is better than CT/MRI in finding recurrent oral cancer

Cincinnati Children's Research Foundation - Neonatal methamphetamine exposure has long-term effects on cognitive function

Columbia University - Future of research on eating disorders reviewed

Corixa Corp., Seattle - Mammaglobin may be a candidate diagnostic marker for breast cancer

Ctr. for DNA Fingerprinting & Diagnos., Hyderabad -  M. tuberculosis thioredoxin reductase characterized

Cutting Edge Information - Clinical trials target specific ethnic groups

Cutting Edge Information - Patient non-compliance caused by lack of communication

Cutting Edge Information - Report looks at patient compliance

Design Continuum - Human factors engineer to address obesity trends, treatments, and prevention

Digital Gene Technology Inc. - Exploiting immune surveillance leads to new mucosal vaccines

Dongeui University, Pusan - Wikyungtang herb inhibits proliferation of lung cancer cells in vitro

Emory University - Interleukin-8 is a key mediator of breast cancer invasion and angiogenesis

Epimmune, Inc. - Pharmaceutical company completes private placement

First Horizon Pharmaceutical Corp. - Prenate now available in new formula

Fischer Imaging Corp. - Imaging company completes restatement, files audited statements for 2000-2003

Fox Chase Cancer Center - Metastatic/examined lymph node ratio is important prognostic factor

Fred Hutchinson Cancer Research Center - LCR promotes beta-globin transcription repression in committed cells

Friedrich-Loeffler-Institutes - Deletion of pseudorabies virus proteins impairs secondary envelopment

Genesis Medical Center, Davenport - Pacemakers and defibrillators can be implanted with ongoing warfarin therapy

Genzyme Corp. - Renagel maker reports financial results for first quarter

George Washington University - Sex steroids influence the effects DHEA has on cognition in menopausal women

Georgetown University - Quicker testing for BRCA genes available - at a price

GlaxoSmithKline - New dosage strength approved for ZANTAC EFFERdose Tablets

Gunma University - Sodium selenite has potent antimalarial activity

Hadassah University Hospital - IL-2 improves metastatic malignant melanoma response to vaccine

Hormone Replacement Therapy - Group comments on results of WHI estrogen-only study

Hydron Technologies, Inc. - Technology company reports drop in net sales for quarter, year

Idenix Pharmaceuticals, Inc. - 1-year results announced for Telbivudine hepatitis B treatment candidate

Immune Response Corporation - Preclinical data support continued development of IR103 HIV drug candidate

Indiana University - Parents play key role in vaccinating adolescents against STDs

Institute for Cancer Research, Surrey - Biallelic MYH mutations confer susceptibility to colorectal cancer

Institute of Biotechnology and Antibiotics - Inclusion bodies from recombinant bacteria deliver vaccine antigen

Introgen Therapeutics, Inc. - National Cancer Institute grant to fund phase II study of INGN 241

Japanese Foundation for Cancer Research - Murine hepatitis models can screen for Cav 1.3-specific therapy

Jerini, AG - Company announces positive results in bioavailability study for Icatibant

Kansai Medical University - Perillyl alcohol suppresses breast cancer cell growth in vitro and in vivo

Kyoto University - Treatment options for adult T-cell leukmia reviewed

Laser Diagnostic Technologies, Inc. - GDxVCC maker announces revenue growth

Lifecore Biomedical, Inc. - Biomedical company reports record net sales in third quarter

London School of Hygiene & Tropical Medicine - Doctors' reluctance to ask parents to consent to postmortems may be misplaced

Lund University - Novel ELISA detects Shiga toxin-producing E. coli in children

MDS Pharma Services - Companies team to offer ABC transporter assays

MGI Pharma, Inc. - Pharmaceutical company reports first quarter 2004 financial results

Mayo Clinic - Discovery sheds light on how cancer cells grow and divide

Mayo Clinic - EGF-induced mitosis increases SLPI levels in keratinocytes

Medical College of Wisconsin - Common anemia drug may protect infants undergoing heart surgery

Medical Discoveries, Inc. - Additional secured debt eliminated; MDI-P development continues

Medical Malpractice - Florida Senate: No lawsuit protection for mammogram readers

Medtronic, Inc. - Pivotal clinical trial for Intercept Epilepsy Control System begins

Memorial Sloan-Kettering Cancer Center - A multidisciplinary approach is necessary when treating thyroid cancer

Memorial Sloan-Kettering Cancer Center - Sentinel lymph node biopsy may raise threshold for adjuvant therapy

Nagoya University - Hormone modifications due to pregnancy may reduce colon cancer risk

National Brain Research Center, Manesar - Curcumin induces apoptosis via impairment of the ubiquitin-proteasome system

National Cheng Kung University - Impedance method effective for Pseudomonas aeruginosa subtyping

National Council for Scientific Research - Findings boost idea that Neanderthals distinct from humans

Neurochem, Inc. - Positive results announced in on-going phase II extension study for Alzhemed

NicOx S.A. - Alzheimer drug candidate reduces most common form of dementia in elderly

Norak Biosciences, Inc. - Research collaboration to discover and develop novel pharmaceutical compounds

Nymox Pharmaceutical Corp. - Study: Statins boost cognition in the elderly

Orphan Medical, Inc. - Pharmaceutical company announces filing of registration statement

Otto Von Guericke Univ., Magdeburg - Specific oncosurgical therapies are not suited to outpatient clinics

Pennsylvania State University - Moderate iron deficiency affects cognitive performance of young women

Prince of Wales Hospital, Randwick - Researchers study the psychosocial needs of breast cancer survivors

Quest Diagnostics, Inc. - John C. Baldwin, MD, nominated for election to board of diagnostics company

Rabies Prevention - Pennsylvania begins rabies-baiting program earlier this year

Regeneration Technologies, Inc. - Exclusive distribution agreement for spinal implants amended

Research Institute for Tropical Medicine - Varicella and MMR vaccines can be administered together safely

Sangart, Inc. - Swedish MPA issues approval for Hemospan phase II clinical trial

Sanofi-Synthelabo - GlaxoSmithKline to buy Arixtra, Fraxiparine, and manufacturing Plant

Schering, AG, Group - Primovist, a new MRI liver-contrast agent, approved in Sweden

Schering-Plough - Claritin manufacturer posts $73 million first-quarter loss

Scripps Research Institute - Src blockade stabilizes blood vessel mechanisms after a heart attack

Scripps Research Institute - Viral-induced diabetes is accompanied by phagocytosis of beta cells

Shanghai Second Medical University - Reactive oxygen species level determines cell susceptibility to apoptosis

Spectrum Pharmaceuticals, Inc. - Eoquin anti-tumor activity studies initiated in U.S.

Stanford Univ. School of Medicine - For his genetic work with worms, researcher takes prize

Stanford University - Blood screen may help cancer patients thwart radiation side effects

Stanford University - Elusive but ubiquitous microbe fingered as gum disease culprit in Stanford study

Stanford University - Is it right to boost brainpower with implants?

State University of New York, Stony Brook - Membrane lipid composition affects receptor function in Saccharomyces

Sunnybrook & Women's College Hlth Sci Ctr, Toronto - Ring finger protein RNF11 important target for novel cancer therapies

Taichung Veterans General Hospital - Ethanol protects against ischemic brain injury

Tampere University Hospital - PCR TB testing not cost-effective in low-prevalence area

Technical University of Munich - Urokinase-type plasminogen activator is prognostic in breast cancer

Teenage Smoking - Tobacco-prevention ads target teens in North Carolina

The Thomson Corporation - Competitive intelligence provider for pharmaceutical industry acquired

Trestle Holdings, Inc. - University of Michigan Health System purchases live microscopy product

U.S. Centers for Disease Control & Prevention - Nipah virus conforms to rule of six in minigenome replication assay

U.S. Centers for Disease Control & Prevention - Rotavirus typing methods and algorithms reviewed

U.S. National Institutes of Health - Effect of HIV infection on NK cell inhibitory receptors clarified

U.S. National Institutes of Health - Late effects of neck irradiation described

Univ. of North Carolina, Chapel Hill - Researchers focus on impending staffing crisis in nursing homes

Univ. of Texas SW Medical Center - BACE 1 cleaves amyloid-beta precursor protein

Univ. of Texas, Dallas - Two molecules work together to aid transport of immune cells

Universite de la Mediterranee - CRB3 regulates morphogenesis of tight junctions in epithelial cells

University at Buffalo - High-fat breakfast produces rush of inflammatory factors into bloodstream

University of Arizona - The hypoxia-inducible factor-1 inhibitor PX-478 abates large tumor growth

University of Barcelona - Features of HIV- and hepatitis C-related APS described

University of Bordeaux 2 - New Chlamydia trachomatis reference strains will aid Cameroonian labs

University of California, San Diego - Racial distribution of chemokine mutations determined

University of Cambridge - Information supports protective cytokine hypothesis of atherosclerosis

University of Colorado - HLA-DQ8-associated T cell responses to diabetes autoantigen studied

University of Freiburg - Steroidogenic acute regulatory therapy useful for adrenocortical cancer

University of Heidelberg - Ultrasound and DXA osteodensitometry identify women with a risk for bone loss

University of Houston - HIV integrase pharmacophore model developed

University of Iowa - Some infertile couples unaware of multiple birth risks

University of Leeds - Genetic studies may reveal the cause of primary and secondary microcephaly

University of Manitoba - Interferon-alpha inhibits SARS coronavirus

University of Maryland - More than a million Americans abuse prescription drugs

University of Massachusetts - Prohormone convertases I and II implicated in obesity development

University of Miami - RING-finger-like protein Ini1 essential for cell cycling in yeast

University of Michigan - Diagnostic algorithm quickly distinguishes anthrax from flu

University of Michigan - Her-2 and EGFR are osteosarcoma vaccine targets

University of Michigan - Phosphorylated HSP27 essential for association of RhoA with PKC alpha

University of Minnesota - Midwives tend to have good outcomes with vaginal birth after cesarean section

University of Naples Federico II - Autocrine stimulation by osteopontin sustains carcinoma proliferation in vitro

University of North Carolina Hospital - Women with persistent urinary tract infections need in-depth evaluations

University of Pavia - Bone marrow and stem-cell features characterized in RA patients

University of Pittsburgh - Myeloma bone disease destroys bone, which is not replaced

University of Rochester - Brain tumors may depend on multiple variables for growth that are not understood

University of Saarland - Cancer testis antigens show promise for pancreatic carcinoma treatment

University of Sao Paulo - Changes in dietary sodium consumption modulate early insulin signaling

University of Southern Denmark - Overproduction of Lon protease inhibits translation in E. coli

University of Sydney - Noncompliance with immunosuppressive medications can cause organ rejection

University of Texas Southwestern - Fat distribution better predictor of cardiovascular risk and death

University of Toronto - Link recognized between Internet use and cancer outcome

University of Ulm - Role of Bcl10 protein in B-cell development and activity clarified

University of Washington - Determining features of HIV neutralization phenotype identified

University of Washington - Gene mutation found for a form of juvenile-onset motor neuron disease

University of Washington - Vaccine allows for infection control in macaques exposed to SHIV

VIASYS Healthcare - CEO of medical technology company announces new board member

VaxGen, Inc. - New type of anthrax vaccine moves into larger-scale trial

Vencor International, Inc. - Home Access FDA-approved at-home tests to be distributed internationally

Vertex Pharmaceuticals Incorporated - Study results highlight therapies for unmet needs in hepatitis C treatment

Viragen, Inc. - Scottish government awards grant for anti-cancer antibody research

Virginia Pharmacists Association - FDA, HHS, pharmacists distribute educational materials

Vital Signs, Inc. - Medical products manufacturer names VP of global marketing and strategy

Wake Forest University - Temperature and humidity can affect LASIK surgery results

Walter & Eliza Hall Institute of Medical Research - Transcriptional changes during severe malaria identified

Washington University - Protein may help prevent autoimmune attacks

Wayne State University - Mastoparan potentiates NO release from insulin-secreting cells

Weizmann Institute - New imaging approach enables better view of kidnesy

Weizmann Institute Science - DNA vaccination with CD25 protects rats from adjuvant arthritis

Weizmann Institute of Science - Thrifty bacteria use just-in-time ordering

Wyeth - Sales up but profit down compared with last year Effexor maker reports

Wyeth Pharmaceuticals - FDA approves reformulation of Protonix IV for Injection

Yamaguchi University - Angiogenic induction is low with ex vivo expanded CD117+ stem cells

York University - Leptin increases cardiomyocyte hyperplasia

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