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Pharma Investments, Ventures and Law Weekly

Susan Hasty, Publisher

Table of Contents . . . June 20th, 2004

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Pharma Investments, Ventures and Law Weekly | Other Publications

Accelerator Corporation - Two emerging biotech companies get start-up funding

Access Pharmaceuticals, Inc. - Pharmaceutical firm reports loss of $0.17 per share

American Oriental Bioengineering - Chinese biotech firm reports income of $0.04 per share

Amylin Pharmaceuticals, Inc. - Pharmaceutical company files resale registration statement

Antares Pharma, Inc. - Pharmaceutical company reports 20% decrease in revenues

Astralis, Ltd. - Biotech company reports quarterly loss of $0.19 per share

Avax Technologies, Inc. - Biotech company announces agreement for sale of common stock

Avitar, Inc. - Avitar reports second quarter financial results for fiscal 2004

BTG - Novel technique brings prenatal testing from maternal blood closer to reality

BioCryst Pharmaceuticals, Inc. - Pharmaceutical company elects John L. Higgins to board of directors

BioSante Pharmaceuticals - Hormone therapy developer reports loss of $0.17 per share

BioVeris Corporation - Biotech firm added to NASDAQ biotechnology index

Boston Biomedica, Inc. - Biotech, diagnostics services company reports 1.6% decrease in revenue

CalbaTech, Inc. - Life sciences company announces reduction in liabilities

Carrington Laboratories, Inc. - Biopharmaceutical company elects directors, approves stock option plan

454 Life Sciences - $2.4M NIH grant to be used for picoliter-scale sequencing technology

Alere Medical, Inc. - Deal signed for disease management services for Health Options

Alexion Pharmaceuticals, Inc. - Phase III trial of pexelizumab published in JAMA

Applied Imaging Corp. - Imaging systems company reports 10% decrease in revenues

Armed Forces Research Inst. of the Med. Sciences -  Plasmodium vivax transmission and control reviewed

Austin Research Institute - Malaria prime boost vaccines reviewed

Aventis - FDA grants approval for Taxotere in prostate cancer

Axcan Pharma, Inc. - Positive phase II results reported for ITAX

Back Pain - Psychological distress is reliable predictor of back pain, investigation shows

Bellvitge Hospital, Catalonia - Hepatocyte growth factor gene transfer may treat diabetic kidney disease

Biodoxis - Dermatofibrosarcoma protuberans must be distinguished from similar tumors

Bioenvision, Inc. - Clofarabine trial in adult acute leukemia exceeds expectations, closed early

Biomira, Inc. - Spin-off company to develop liposomal interleukin-2 technology

Bioniche Life Sciences, Inc. - Bladder cancer trial data presented to American Urological Association

Biopure Corporation - Oxyglobin maker reports loss of $0.25 per share

Biotherapy - New clinics open to help patients suffering from cancer, inflammation

Brandeis University - Use of human growth hormone for biomedical enhancement examined

CHF Solutions - Service provider relationship deal signed with Fresenius Medical Care

CHU Arnaud Villeneuve - IL-21 is a switch factor for B-cell production of IgG1 and IgG3

Cedars Sinai Research Institute - Mutations in gene encoding filamin B disrupt vertebral segmentation

Centocor, Inc. - Trial to compare biologic therapy with conventional therapy in Crohn disease

Charite University of Medicine, Berlin - Technique helps determine axillary lymph node tumor status in some patients

Children's Hospital, Columbus - Tumor banks provide tissue specimens for research

Chiron Corporation - Mucosal immunization with cholera adjuvant offers long-term immunity

Chonnam National University Hospital - Pacemaker lead endocarditis caused by Achromobacter xylosoxidans reported

Christie Hospital NHS Trust - Candidate factors steer mammary gland hormone receptors towards oncogenesis

Chulalongkorn University - Convective-controlled double high flux hemodiafiltration shows promise

City of Hope, Duarte - Modified vaccinia virus elicits antibodies to cytomegalovirus strains

Cleveland Clinic Foundation - Quality of life is not a treatment selection factor for older cancer patients

Coalition for Pulmonary Fibrosis - Research: 55% of IPF patients may be initially misdiagnosed

Cognis Group - Study: CLA helps overweight adults safely reduce body fat

Columbia Laboratories, Inc. - Pharmaceutical firm raises $6.4M through sale of common stock

Columbia Univ. College of Physicians & Surgeons - Adult living donor liver transplantations have been slow to gain acceptance

Connetics Corporation - U.S. issued patent covers emollient-foam technology

Corgentech, Inc. - Phase I/II trial of E2F Decoy begins for prevention of AV graft failure

Corixa Corporation - Prostate tissue-specific vaccine candidate identified

Danish Institute for Food & Veterinary Research - DNA vaccine may protect piglets against porcine circovirus type 2

Defence R&D Establishment, Gwalior - Sandwich dot-ELISA detects S. pneumoniae in CSF

Drexel University - Intraoperative liver ultrasound is important for hepatic tumor resection

Duke University - Cerebral cavernous malformations stem from primary vascular defects

Duke University - Different methods are needed to modifying attributions of colorectal cancer risk

Eastern Virginia Medical School - Diabetic autonomic neuropathy reviewed

Epidemiology - HIV/AIDS disproportionately affects African American women

Free University of Brussels - Insulin-like growth factor is a comprehensive cytokine in multiple myelomas

Frost & Sullivan - Analysis shows non-fusion spine procedure revenues to total $27M in 2005

G.B. Rossi Polyclinic - Computerized system facilitates drug management

Genaissance Pharmaceuticals, Inc. - FAMILION Test for genetic mutations associated with arrhythmia

Genencor International - Company readies sarin-gas neutralizing enzyme for first responders

GeoPharma, Inc. - Innovative Cos. announces name change

George Washington University Medical Center - Tissue factor could be targeted for thrombosis prevention in cancer patients

Guilford Pharmaceuticals, Inc. - GLIADEL Wafer maker joins NASDAQ Biotech Index

Gulhane Military Medical Academy, Etlik - Antioxidant system activation is important for prostate cancer patients

Gynecologic Cancers - Chemotherapy regimen treats undifferentiated uterine endometrial cancer

Health & Nutrition Systems International, Inc. - Weight-management company reports net loss for quarter

Health Status - New York City health department announces new survey

Healthcare Access - Medical Center serving patients in remote areas through telemedicine technology

Hemispherx Biopharma, Inc. - Alferon-maker reports first quarter results; net loss largely due to financing costs

Hiroshima University - Protein secondary structure analyzed by vacuum-UV circular dichroism

Hoffmann-La Roche, Inc. - Registry data demonstrate superior long-term organ transplant outcomes

Hopital Avicenne, Bobigny - Microvessel density has some prognostic value, study finds

Hypertension Diagnostics, Inc. - Diagnostics company announces third quarter total revenue of $210,521

InKine Pharmaceutical Co., Inc. - Enrollment complete in phase II study of purgative product - INKP-102

InfaCare Pharmaceutical Corp. - John Post named COO of company focused on neonatal and pediatric therapeutics

Institute of Cancer Research, London - Gene portraits profile differences in breast-tumor types

Interleukin Genetics, Inc. - Genetics company receives two patents related to inflammation

Johann Wolfgang Goethe-University - Mechanical pressure-induced phosphorylation of protein kinase reported

John Hunter Hospital, Newcastle - Pregnant woman's asthma is likely to be worse if baby is a girl

Johns Hopkins University - EBV-induced growth proliferation inhibited by nuclear antigen EBNA2-TAT peptide

Juvaris BioTherapeutics, Inc. - Company gets grant for development of P. aeruginosa vaccine

Kantonsspital Basel - Cardiovascular research now involves proteomics

Kumamoto University - CHOP-induced apoptosis mediated by Bax translocation from mitochondrial cytosol

Laboratory Corp. of America Holdings - New noninvasive swab test for AAT deficiency offered

Legal Issues - Two more former Rite Aid executives sentenced

M.D. Anderson Cancer Center - Low-dose alemtuzumab reduces GVHD following myeloablative ASCT

M.D. Anderson Cancer Center - Researchers review spirituality among gynecological cancer patients

M.D. Anderson Cancer Center - Retinoid-modulated proteins identified in squamous carcinoma cells

M.D. Anderson Cancer Center - Stat3 activation may be a critical event during skin tumor promotion

Mayo Clinic - Abdominal fat increases FFA distribution to liver, especially in women

Mayo Clinic - Influence of HLA-DRB1 alleles on immune responses to measles examined

McMaster University - Heightened tissue factor expression is implicated in oncogenic events

Medco Health Solutions - Pediatric spending spike on drugs to treat behavioral problems

Mental Health - Arkansas ends treatment for mentally ill acquitted of crimes

MorphoSys, AG - Novartis enters strategic antibody alliance

Nagasaki University - Isoflavones stimulate estrogen receptor-mediated core histone acetylation

National Cancer Center of Singapore - Combined tamoxifen-quercetin therapy eliminates prostate cancer tumors

National Cardiovascular Center, Osaka - Effects of ICAM-1 g.1548G>A mutation characterized

National Inst. of Standards & Technology - Tools for reliable "gene chip" measurements in development

National Taiwan University - Expression of genes in differentiating adipocytes characterized

National Tsing Hua University - Crosslinking determines degradation rate and regeneration of acellular tissue

National University Hospital of Singapore - Brachytherapy after chemoradiation for nasopharyngeal cancer reported

National University of San Luis - High prevalence of H. pylori contact in Argentina

National Yang Ming University - New protein constructs stymie hepatitis D virus RNA editing

Natural Balance, Inc. - Nutraceutical completes acquisition of supplement maker

New York University - Neuropathology assessed in mouse model of Alzheimer disease

North Shore Hospital, Auckland - Perioperative beta blocker use is inconsistent in heart disease patients

Northfield Laboratories, Inc. - PolyHeme maker added to Nasdaq Biotech Index

Northwestern University - Human lymphocytes not susceptible to simian virus 40 infection

Norwood Abbey, Ltd. - Rolf Stahel named as nonexecutive chairman of immunology company

Novartis - Study counters perceptions about treating hypertension in blacks

Novartis AG - Single infusion of zoledronic acid effective in Paget disease trial

Oregon Health & Science University - Epithelial cell expression upon Neisseria infection studied

Oregon3D, Inc. - 3D models being used to determine gene development in heart

Osaka City University - Cisplatin combined with weekly paclitaxel is active against advanced NSCLC

PURE Bioscience - Products using axenohl silver dihydrogen citrate technology under development

Pennsylvania State University - Release of iron from ferritin is an important part of the nicking mechanism

Prescription Drug Cost - Panel hears arguments over cost of AIDS drug

Procter and Gamble Co. - Handwashing program decreases incidence of diarrhea among children in Pakistan

Questcor Pharmaceuticals, Inc. - Pharmaceutical company announces election of directors

RIKEN, Saitama - mtDNA 10398 polymorphism related to maintenance lithium treatment response

Respironics, Inc. - Acquisition offer announced for Profile Therapeutics

Roche - Pharmaceutical company establishes foundation for anemia research

Roswell Park Cancer Institute - Benign liver tumors are found more frequently with abdominal imaging

Rotavirus Vaccine Program - Surveillance planned in Asia for devastating diarrheal disease in children

Royal Children's Hospital, Victoria - Guideline evaluates treatment of infantile spasms

Rush-Presbyterian-St. Luke's Medical Center - Anterolateral mini-incision total hip replacement reviewed

SRI International - Grant awarded to expand development of metabolic pathway database

Scripps Research Institute - Aminoglycoside array enables high-throughput analysis of RNA interactions

Selas Corporation of America - Medical product manufacturer reports first quarter financial results

Shiga University of Medical Science - C-reactive protein may be an important marker for arterial stiffness

Shinshu University - Cold compresses effective for pain relief after total hip replacement

Signet Laboratories, Inc. - Diagnostics/research company Launches eCommerce site

Silicon Graphics, Inc. - Altix system helps cancer center accelerate computational disease research

Sontra Medical Corp. - Gerard E. Puorro and Brian F. Sullivan join board of SonoPrepmaker

St. Francis Hospital, Mooresville - Variables affecting post-TKA range of motion identified

St. George Hospital, London - Radiotherapy alone for early-stage NHL is inferior to chemotherapy

St. Jude Children's Hospital - Cell-signaling drugs show promise for treating medulloblastoma

St. Jude Medical Inc. - Implantable cardioverter defibrillator study results released

St. Jude Medical, Inc. - New lead delivery tools launched for cardiac resynchronization therapy

St. Mary's Hospital, Manchester - Baby born from sperm frozen for record 21 years

Staffing - University of Maryland School of Medicine adding 100 scientists

State University of New York, Stony Brook - Selective permeability of gap junction channels reviewed

SuperGen, Inc. - Nipent may facilitate hematopoietic stem cell transplantation, study shows

Technical University of Munich - Redox balance shifts remodeling processes during pulmonary hypertension

The Children's Hospital of Philadelphia - Gene discovered for debilitating Cornelia de Lange syndrome

Trimeris, Inc. - Data on first Fuzeon international consensus guidelines published

U.S. Centers for Disease Control & Prevention - Reptile and amphibian contact increases risk of salmonellosis

U.S. Centers for Disease Control & Prevention - Rubella virus capsid protein modulates virus infectivity

U.S. Food & Drug Administration - Clinical proteomics is revolutionizing disease detection

U.S. Food & Drug Administration - Molecular typing methods for E. coli O157:H7 isolates evaluated

U.S. Military Academy - Silver plus UV radiation may prove more effective at disinfecting water systems

U.S. National Cancer Institute - Ravuconazole lysine phosphoester effective against pulmonary aspergillosis

U.S. National Institutes of Health - Respiratory syncytial virus proteins suppress induction of interferons

UVSolutions - Patent granted for germicidal device to prevent nosocomial infections

Umea University - Method to load antigen-presenting protein with glycolipids developed

Univ. of California, San Diego - Study shows misunderstanding, misuse of common OTC medication for UTI

Univ. of Southern California - Eating some types of fish during pregnancy may protect baby from future asthma

Univ. of Texas SW Medical Center - Orexin peptides prevent cataplexy in narcolepsy model

Univ. of Washington School of Medicine - Obesity may affect accuracy of mammography

University College London - Treatment with arimoclomol delays disease progression in ALS mice

University at Buffalo - Underserved use alternative therapies at same rate as general population

University of Bonn - Dogma destroyed: "Neural glue" can communicate!

University of Bonn - Hepatitis C-derived lipopeptides induced antibody-producing T cells

University of Cambridge - NP- and PB1-binding sites of influenza A virus PB2 protein identified

University of Cambridge - Streptococcal inhibitor of complement interactions investigated

University of Cologne - Histone-like nucleoid structuring protein represses E. coli operon

University of Colorado - Increased vascular HO-1 expression contributes to vasodilation in cirrhotic rats

University of Colorado - Novel method for measuring multiple cytokines from small samples

University of Erlangen - Exercising after menopause may help reduce bone loss

University of Heidelberg - Cholesterol modulates P-glycoprotein activity in human PBMC

University of Iowa - The thyroxine analog DITPA modifies post-infarction myocardial remodeling

University of Maryland - Glycoprotein inhibition by indole-3-carbinol may hold therapeutic promise

University of Maryland - IAP expression induces intestinal epithelial cells to resist apoptosis

University of Michigan - Antibiotics alter microbes in GI tract, increase lung sensitivity to allergens

University of Naples Federico II - Formation of disulfide bonds in Ig Fc assisted by protein-disulfide isomerase

University of Naples Federico II - Pituitary tumors with D-2 receptor activity respond to cabergoline therapy

University of North Carolina - Study reviews modern hepatic imaging

University of Pittsburgh - A novel genetically engineered marker keeps track of stem cells in vivo

University of Porto - Telomerase inhibition is a cancer therapy that is not always what it seems

University of Reading - M1 matrix protein controls filamentous phenotype of influenza A virus

University of Sao Paulo - Latissimus dorsi muscle changes impair cardiomyoplasty in diabetes

University of Southampton - Meningococcal PorA protein induces bactericidal immune response

University of Texas Southwestern - Many patients take more pain relievers than recommended

University of Tokyo - Female IQI/Jic mice useful for study of contact dermatitis

University of Toronto - NEDD8 regulates von Hippel-Lindau-related tumorigenesis

University of Turin - Tailored schedules may help retain residual renal function

University of Urbino - Patient, disease, and treatment factors predict docetaxel-related toxicity

University of Utrecht - Live attenuated coronavirus vaccines protect against feline peritonitis

University of Vienna - Flavaglines induce apoptosis in colorectal cancer cells

University of Vienna - IFN resistance promotes oncolysis by influenza virus NS1-deletion mutants

University of Virginia - Autoimmune diabetes is blocked in stat4-deficient mice

University of Washington - Intercellular signaling pathways influence neuromuscular development

University of Western Ontario - LF15-0195 inhibits NF-kappaB signaling through IKK suppression

University of the Studies of Rome, La Sapienza - Virus-specific regulatory T cells counteract anti-hepatitis C virus response

Utrecht University - Cytokine responses to inactivated viruses fail to default without IL-12

Vitra Bioscience, Inc. - Encoded microcarriers enable simultaneous analysis of multiple cell types

Washington Hospital Center - Drug ineffective in reducing complications after irradiation

World Health Organization - World surveys find mental disorders highly prevalent and often untreated

Yale University - CREB binds to multiple loci on chromosome 22

Yale University - Everolimus safe and effective immunosuppressant in organ transplantation

Zhejiang University - Vector of membrane fusogenic liposomes used for melanoma vaccine

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